Evidence map›Paper›PMID 40177701›Full record

ArticleIBRO neuroscience reports2025

N-acetyl-L-cysteine mitigates diabetes-induced impairments in sciatic nerve.

Sukhdev S Kamboj, Satya P Sharma, Wael M Y Mohamed, Rajat Sandhir

Abstract read
In one paragraph

Article in IBRO neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sukhdev S KambojDepartment of Biochemistry, Basic Medical Science Block II, Panjab University, Chandigarh 160014, India.
Satya P SharmaDepartment of Biochemistry, Basic Medical Science Block II, Panjab University, Chandigarh 160014, India.
Wael M Y MohamedDepartment of Basic Medical Sciences, International Islamic University Malaysia, Kuala Lumpur 50728, Malaysia.
Rajat SandhirDepartment of Biochemistry, Basic Medical Science Block II, Panjab University, Chandigarh 160014, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic neuropathy is a consequence of long-term hyperglycemia. The emergence of neuronal condition is a result of hyperglycemia-induced oxidative stress. In the present study, streptozotocin-induced diabetes exhibited notable decrease in the levels of phospholipids, glycolipids, gangliosides, and triglycerides in the sciatic nerve. The alterations in lipids resulted in increase in cholesterol to phospholipid ratio in sciatic nerve of diabetic animals. This ratio is crucial and determines the rheological properties of membranes and resulted in substantial reduction in the activity of membrane-bound enzymes; Ca

Indexed as

DiabetesEnzymesLipidsN-acetylcysteineNeuropathySciatic Nerve. Membrane

Identifiers

PMID40177701
PMCPMC11964552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.