Evidence map›Paper›PMID 40177662›Full record

ArticlePNAS nexus2025

The future potential of controlled environment agriculture.

Vanesa Calvo-Baltanás, Andreas Vilcinskas, Thomas Brück, Werner Kloas, Thomas Wilke, Mariana Rufino, Marius Henkel, Holger Zorn, Oscar Monje, Senthold Asseng

Abstract read
In one paragraph

Article in PNAS nexus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vanesa Calvo-BaltanásTUM CREATE, 1 Create Way #10-02 Create Tower, 138602 Singapore, Singapore.ORCID https://orcid.org/0000-0003-1348-8503
Andreas VilcinskasBranch for Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Ohlebergsweg 12, 35392 Giessen, Germany.ORCID https://orcid.org/0000-0001-8276-4968
Thomas BrückTUM CREATE, 1 Create Way #10-02 Create Tower, 138602 Singapore, Singapore.ORCID https://orcid.org/0000-0002-2113-6957
Werner KloasDepartment of Fish Biology, Fisheries and Aquaculture, Leibniz-Institute of Freshwater Ecology and Inland Fisheries, Müggelseedamm 310, 12587 Berlin, Germany.
Thomas WilkeDepartment of Animal Ecology and Systematics, Justus Liebig University Giessen, Heinrich-Buff-Ring 26, D-35392 Giessen, Germany.ORCID https://orcid.org/0000-0001-8263-7758
Mariana RufinoCellular Agriculture, TUM School of Life Sciences, Technical University of Munich, Gregor-Mendel-Str. 4, 85354 Freising, Germany.
Marius HenkelCellular Agriculture, TUM School of Life Sciences, Technical University of Munich, Gregor-Mendel-Str. 4, 85354 Freising, Germany.ORCID https://orcid.org/0000-0002-5343-9661
Holger ZornBranch for Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Ohlebergsweg 12, 35392 Giessen, Germany.ORCID https://orcid.org/0000-0002-8383-8196
Oscar MonjeAetos Systems Inc., Air Revitalization Lab, Kennedy Space Center, Merritt Island, FL 32899, USA.ORCID https://orcid.org/0000-0002-3371-6043
Senthold AssengTUM CREATE, 1 Create Way #10-02 Create Tower, 138602 Singapore, Singapore.ORCID https://orcid.org/0000-0002-7583-3811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The production of high-quality food needs to increase to feed the growing global population. Controlled environment agriculture (CEA) systems in a vertical farm setting-in which several layers are stacked above each other, thus increasing the area for growth-can substantially boost productivity for crops, algae, mushrooms, fish, insects, and cultured meat. These systems are independent of climate, weather, and region, offering reduced environmental impact, although they come with high energy demands. An easy-to-understand, quantitative performance assessment of the theoretical potential for these 6 CEA systems is proposed here. It compares them against the world's main food production system: field production of maize, wheat, rice, and soybean. CEA could play a pivotal role in the global food supply if efficiencies in energy, control of growth environments, and waste stream utilization are vastly improved. Technological advancements, targeted policy support and public engagement strategies will be necessary to significantly reduce production costs and increase public acceptance.

Identifiers

PMID40177662
PMCPMC11961353

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.