Evidence map›Paper›PMID 40177616›Full record

ArticleHemaSphere2025

H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape in preleukemia and B cell acute lymphoblastic leukemia.

Vera H Jepsen, Andrea Hanel, Daniel Picard, Rigveda Bhave, Rebecca Hasselmann, Juha Mehtonen, Julian Schliehe-Diecks, Carla-Johanna Kath, Vithusan Suppiyar, Yash Prasad and 18 more

Abstract read
In one paragraph

Article in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Vera H JepsenDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.ORCID 0000-0003-4174-7568
Andrea HanelInstitute of Biomedicine, School of Medicine University of Eastern Finland Kuopio Finland.
Daniel PicardDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Rigveda BhaveDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.ORCID 0009-0001-8923-2670
Rebecca HasselmannDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Juha MehtonenInstitute of Biomedicine, School of Medicine University of Eastern Finland Kuopio Finland.
Julian Schliehe-DiecksDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Carla-Johanna KathDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Vithusan SuppiyarGerman Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf Düsseldorf Germany.
Yash PrasadDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Katerina SchaalDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Jia-Wey TuDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Nadine RüchelDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Ersen KameriDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Nan QinDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Herui WangNeuro-Oncology Branch, Center for Cancer Research National Cancer Institute, NIH Bethesda Maryland USA.
Zhengping ZhuangNeuro-Oncology Branch, Center for Cancer Research National Cancer Institute, NIH Bethesda Maryland USA.
Rabea WagenerDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Lena BlümelDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Tobias LautweinGenomics Transcriptomics Laboratory, Biomedical Research Center Heinrich Heine University Düsseldorf Germany.
Daniel HeinDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
David KoppsteinGerman Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf Düsseldorf Germany.
Gesine KöglerCenter for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD) Bonn Germany.
Marc RemkeDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Sanil BhatiaDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.
Merja HeinäniemiInstitute of Biomedicine, School of Medicine University of Eastern Finland Kuopio Finland.
Arndt BorkhardtDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.ORCID 0000-0002-6121-4737
Ute FischerDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty Heinrich Heine University Düsseldorf Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40177616
PMCPMC11962653

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.