Evidence map›Paper›PMID 40177432›Full record

ArticleCureus2025

A Rare Case of Gastropleural Fistula During Chemotherapy for Metastatic Colorectal Cancer.

Yoko Shono, Akinori Sekioka, Tetsuo Ito, Kunihiko Tsuboi, Shuichi Ota

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yoko ShonoGastroenterological Surgery, Osaka Saiseikai-Noe Hospital, Osaka, JPN.
Akinori SekiokaGastroenterological Surgery, Osaka Saiseikai-Noe Hospital, Osaka, JPN.
Tetsuo ItoGastroenterological Surgery, Osaka Saiseikai-Noe Hospital, Osaka, JPN.
Kunihiko TsuboiGastroenterological Surgery, Osaka Saiseikai-Noe Hospital, Osaka, JPN.
Shuichi OtaGastroenterological Surgery, Osaka Saiseikai-Noe Hospital, Osaka, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastropleural fistula (GPF) is a rare and life-threatening condition, often associated with peptic ulcer disease, trauma, abscess, malignancies, prior surgeries, or chemoradiation therapy. Its rarity, diverse clinical presentations, and the general condition of affected patients make GPF challenging to diagnose and treat. We present a case of GPF occurring during chemotherapy with anti-vascular endothelial growth factor (anti-VEGF) therapy for stage IV colon cancer with multiple peritoneal metastases. The patient underwent surgical repair of the fistula four weeks after the last administration of anti-VEGF therapy. Postoperative recovery was uneventful, and the patient successfully resumed oral intake. To the best of our knowledge, this is the first reported case of GPF in the context of stage IV colon cancer. This case highlights the importance of selecting an appropriate timing for surgical intervention, taking into account the patient's overall condition and treatment history.

Indexed as

anti-vascular endothelial growth factorchemotherapycolorectal cancergastropleural fistulaperitoneal metastases

Identifiers

PMID40177432
PMCPMC11962330

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.