Evidence map›Paper›PMID 40177355›Full record

ArticleFrontiers in physiology2025

The effects of eccentric cycling on vascular reactivity.

Manuel Gomez, Samuel Montalvo, Daniel Conde, Gabriel Ibarra-Mejia, Alvaro N Gurovich

Abstract read
In one paragraph

Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manuel GomezClinical Applied Physiology Laboratory, Department of Physical Therapy and Movement Science, The University of Texas at El Paso, El Paso, TX, United States.
Samuel MontalvoStanford Sports Cardiology, Division of Cardiovascular Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.
Daniel CondeClinical Applied Physiology Laboratory, Department of Physical Therapy and Movement Science, The University of Texas at El Paso, El Paso, TX, United States.
Gabriel Ibarra-MejiaBioErgonomics Laboratory, Department of Public Health Sciences, The University of Texas at El Paso, El Paso, TX, United States.
Alvaro N GurovichClinical Applied Physiology Laboratory, Department of Physical Therapy and Movement Science, The University of Texas at El Paso, El Paso, TX, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Eccentric cycling has gained attention as a novel exercise modality that increases muscle performance at lower metabolic demand, which could enhance cardiovascular rehabilitation. However, endothelial function response to eccentric cycling (ECC) has yielded contradictory results. Therefore, the purpose of this study was to determine the effect of 30 min of moderate-intensity cycling ECC on endothelial function. Methods: A total of 15 (9 females, 6 males) young, apparently healthy participants were recruited for two laboratory visits. First, a maximum oxygen consumption (VO Results: There was a significant increase in endothelial function (p = 0.037) when adjusting pre-exercise baseline diameter to adjust for ESS, but when utilizing the traditional method no change in endothelial function was observed. Conclusion: 30-min of moderate ECC showed a significant improvement in endothelial function when accounting for exercise-induced ESS. These results support the use of the pre-exercise baseline diameter when calculating post-exercise FMD to avoid the exercise-induced ESS or muscle metabolites effects on post-exercise artery diameter.

Indexed as

eccentric cyclingendothelial functionendothelial shear stressexercise-inducedflow-mediated dilation

Identifiers

PMID40177355
PMCPMC11961952

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.