Evidence map›Paper›PMID 40177282›Full record

ArticleFrontiers in medicine2025

Case Report: Tattoo sarcoidosis with epithelioid cell granuloma positive for

Yuiko Masuda, Hiroko Okabayashi, Kimitaka Akaike, Shohei Hamada, Aiko Masunaga, Hidenori Ichiyasu, Kenichi Ohashi, Takuro Sakagami

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuiko MasudaDepartment of Respiratory Medicine, Kumamoto University Hospital, Faculty of Life, Sciences, Kumamoto University, Kumamoto, Japan.
Hiroko OkabayashiDepartment of Respiratory Medicine, Kumamoto University Hospital, Faculty of Life, Sciences, Kumamoto University, Kumamoto, Japan.
Kimitaka AkaikeDepartment of Respiratory Medicine, Kumamoto University Hospital, Faculty of Life, Sciences, Kumamoto University, Kumamoto, Japan.
Shohei HamadaDepartment of Respiratory Medicine, Kumamoto University Hospital, Faculty of Life, Sciences, Kumamoto University, Kumamoto, Japan.
Aiko MasunagaDepartment of Respiratory Medicine, Kumamoto University Hospital, Faculty of Life, Sciences, Kumamoto University, Kumamoto, Japan.
Hidenori IchiyasuDepartment of Respiratory Medicine, Kumamoto University Hospital, Faculty of Life, Sciences, Kumamoto University, Kumamoto, Japan.
Kenichi OhashiDepartment of Human Pathology, Institute of Science Tokyo, Tokyo, Japan.
Takuro SakagamiDepartment of Respiratory Medicine, Kumamoto University Hospital, Faculty of Life, Sciences, Kumamoto University, Kumamoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Tattoo sarcoidosis is characterized by a granulomatous reaction localized to the tattoo site and typical systemic symptoms of sarcoidosis. Herein, we report the case of a patient diagnosed with tattoo sarcoidosis. Case report: A 28-year-old man presented with subcutaneous nodules at two tattoo sites, bilateral hilar and mediastinal lymphadenopathy, multiple micronodules predominantly in the upper lobes of both lungs, elevated serum angiotensin-converting enzyme and soluble interleukin-2 receptor levels, hypercalcemia, and renal dysfunction. Skin biopsy of a subcutaneous nodule revealed epithelioid cell granulomas. Although periodic acid-Schiff, Grocott methenamine silver, and acid-fast staining showed negative results, antibody staining for Conclusion: The pathogenesis of tattoo sarcoidosis remains unknown, although an immune response to tattoo pigments has been suspected. However, there is a theory that

Indexed as

Cutibacterium acnesPropionibacterium acnessarcoidosistattootattoo sarcoidosis

Identifiers

PMID40177282
PMCPMC11962038

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.