Evidence map›Paper›PMID 40177251›Full record

ArticleFrontiers in aging neuroscience2025

Preserved learning despite impaired short-term memory in older adults with mild cognitive impairment.

Elaina Smith, Christopher Cortez, April Wiechmann, Sandra Davis, Hannah Dyson, Krystyn Kucharski, Sarah Ross, Geoffrey Kline, Robert T Mallet, Xiangrong Shi

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elaina SmithDepartment of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, United States.
Christopher CortezDepartment of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, United States.
April WiechmannDepartment of Internal Medicine, University of North Texas Health Science Center, Fort Worth, TX, United States.
Sandra DavisDepartment of Internal Medicine, University of North Texas Health Science Center, Fort Worth, TX, United States.
Hannah DysonDepartment of Internal Medicine, University of North Texas Health Science Center, Fort Worth, TX, United States.
Krystyn KucharskiDepartment of Internal Medicine, University of North Texas Health Science Center, Fort Worth, TX, United States.
Sarah RossDepartment of Internal Medicine, University of North Texas Health Science Center, Fort Worth, TX, United States.
Geoffrey KlineDepartment of Internal Medicine, University of North Texas Health Science Center, Fort Worth, TX, United States.
Robert T MalletDepartment of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, TX, United States.
Xiangrong ShiDepartment of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, United States.

Funding

Intermittent Hypoxia Training: A Novel Therapy for Mild Cognitive ImpairmentR01AG076675 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI SHI, XIANGRONG · 2022 to 2024
$2.1M
NIA NIH HHS R01 AG076675
6 · The paper itself

Abstract

Background: The impact of amnestic mild cognitive impairment (aMCI) on short-term memory (STM) and learning performance assessed with different memory modalities was unknown. This study examined differences in STM and learning ability between verbal and visuospatial memory-modalities in older adults with aMCI. Methods: Thirty-nine aMCI subjects (71.5 ± 6.0 yrs) and 33 non-MCI (control) subjects (71.1 ± 5.7 yrs) of similar age and educational attainment consented to participate in the study. Short-term memory was assessed using Digit-Span-Test (DST), California-Verbal-Learning-Test-2nd edition - short-form (CVLT-II), and Brief-Visuospatial-Memory-Test-Revised (BVMT-R); CVLT-II and BVMT-R assessed verbal-and visuospatial-learning, respectively. Results: DST-Backward ( Significance: Amnestic MCI subjects have diminished STM but intact learning ability. Differences in STM of older adults with vs. without aMCI are more readily distinguished by word-verbal memory and/or visuospatial memory testing than digit-verbal memory testing.

Indexed as

brief visuospatial memory testCalifornia verbal learning testdigit span testlearningworking memory

Identifiers

PMID40177251
PMCPMC11961900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.