ArticlePreventive medicine reports2025
The shifting global landscape of low Back pain attributable to high body mass index: Burden, growth, and inequalities.
Article in Preventive medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Evolving Landscape of Regenerative Therapies: Cell-Based and Cell-Free Approaches for Chronic Low Back Pain.Journal of clinical medicine · 2026Review
- [Analysis of disease burden, attributable risk factors of low back pain in China from 1990 to 2023 and prediction for 2030].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Article
- Machine learning-based prediction of disability in subacute low back pain: a primary care study on clinical and psychosocial determinants.BMC medical informatics and decision making · 2026Observational
- The burden of low back pain and predictions in Asia-Pacific region, 1990-2021: a comparative analysis of China, Japan, Thailand, and Pakistan.Frontiers in medicine · 2026Article
- Dissecting the Genetic Basis of Low Back Pain Independent of BMI Through Genomic Structural Equation Modeling.Journal of pain research · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Low back pain (LBP) is the leading global cause of years lived with disability (YLD), with high body mass index (BMI) recognized as a significant and modifiable risk factor. While prior research has linked high BMI to LBP, comprehensive global assessments of the burden attributable to high BMI are scarce. Methods: We analyzed data from the Global Burden of Disease (GBD) study (1990-2021) to estimate global and regional YLDs of LBP attributable to high BMI, stratified by age, sex, and socio-demographic index (SDI). The Autoregressive Integrated Moving Average (ARIMA) model projected the future burden to 2050. Results: From 1990 to 2021, global YLDs of LBP attributable to high BMI nearly doubled, reaching 8.4 million (95 % uncertainty interval: 0.8-17.4), with an age-standardized rate of 97.7 per 100,000. Burdens rose across all regions, with the steepest increases in middle- and lower-SDI areas. Women consistently experienced nearly double the burden compared to men. High-income North America had the largest YLD counts, while South Asia showed the fastest growth. YLDs peaked among individuals aged 40-70, with an emerging burden in the 20-40 age group. Projections suggest disproportionate increases in high- and high-middle-SDI regions by 2050. Conclusion: The rising burden of LBP attributable to high BMI underscores the urgent need for targeted public health strategies. Integrating BMI management and musculoskeletal health initiatives into healthcare policies could mitigate LBP-related disability and enhance global population health outcomes.
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