Evidence map›Paper›PMID 40177147›Full record

ReviewEcancermedicalscience2025

Breast cancer in Cape Verde: a 24-year retrospective study of clinical presentation, treatment and outcomes at Agostinho Neto University Hospital.

Pamela Borges, Hirondina Borges Spencer, Stefani Furtado, Victor Costa, Carla Barbosa, Lúcio Lara Santos

Abstract readReview
In one paragraph

Review in Ecancermedicalscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pamela BorgesMolecular Biology Laboratory, Agostinho Neto University Hospital, Praia, Plateau PC-112, Cabo Verde.
Hirondina Borges SpencerServiço de Oncologia, Agostinho Neto University Hospital, Praia, Plateau PC-112, Cabo Verde.
Stefani FurtadoMolecular Biology Laboratory, Agostinho Neto University Hospital, Praia, Plateau PC-112, Cabo Verde.
Victor CostaServiço de Cirurgia, Agostinho Neto University Hospital, Praia, Plateau PC-112, Cabo Verde.
Carla BarbosaServiço de Patologia, Agostinho Neto University Hospital, Praia, Plateau PC-112, Cabo Verde.
Lúcio Lara SantosExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Porto 4200-072, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Breast cancer is a significant health concern in Cape Verde, but comprehensive data on its presentation, management and outcomes are limited. This study aims to provide insights into breast cancer patterns in this island nation. Methods: We conducted a retrospective analysis of 586 breast cancer patients treated at Agostinho Neto University Hospital in Praia, Cape Verde, from January 2000 to May 2024. Data on demographics, clinical presentation, diagnostic methods, treatment modalities and survival outcomes were collected and analysed. Results: The study population comprised 578 (98.6%) females and 8 (1.4%) males. The mean age at diagnosis was 52.1 years (SD 13.6) for females and 70 years (SD 16.7) for males. Stage III was the most common presentation (39.4%). Invasive ductal carcinoma was the predominant histological type. Immunohistochemical analysis in 307 patients revealed 69.4% luminal, 26.1% triple-negative and 4.6% HER2-positive subtypes. Treatment primarily involved surgery combined with chemotherapy and/or hormone therapy, with 33.4% receiving radiotherapy. The median follow-up was 36.5 months (range: 1-298 months), and the median survival time was 137.1 months. Conclusion: This study reveals breast cancer patterns in Cape Verde that share similarities with other African nations, including younger age at diagnosis and higher rates of late-stage presentation compared to Western countries. However, encouraging trends in survival outcomes and diagnostic capabilities were observed. These findings highlight the need for improved early detection strategies and expanded access to comprehensive treatment modalities, particularly radiotherapy, in Cape Verde.

Indexed as

breast cancerCape Verdeepidemiologymolecular subtypessurvival

Identifiers

PMID40177147
PMCPMC11959127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.