Evidence map›Paper›PMID 40177110›Full record

ArticleBioactive materials2025

Protein to biomaterials: Unraveling the antiviral and proangiogenic activities of Ac-Tβ

Khandoker Asiqur Rahaman, Md Sofequl Islam Mukim, Md Lemon Hasan, Hyeok Kim, Cheol-Ho Pan, Oh-Seung Kwon, Dae-Geun Song, Hyung-Seop Han

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khandoker Asiqur RahamanCenter for Biomaterials, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
Md Sofequl Islam MukimCenter for Natural Product Systems Biology, KIST Gangneung Institute of Natural Products, Gangneung, 25451, Republic of Korea.
Md Lemon HasanCenter for Biomaterials, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
Hyeok KimCenter for Biomaterials, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
Cheol-Ho PanCenter for Natural Product Systems Biology, KIST Gangneung Institute of Natural Products, Gangneung, 25451, Republic of Korea.
Oh-Seung KwonDoping Control Center, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
Dae-Geun SongCenter for Natural Product Systems Biology, KIST Gangneung Institute of Natural Products, Gangneung, 25451, Republic of Korea.
Hyung-Seop HanCenter for Biomaterials, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptide metabolites are emerging biomolecules with numerous possibilities in biomaterial-based regenerative medicine due to their inherent bioactivities. These small, naturally occurring compounds are intermediates or byproducts of larger proteins and peptides, and they can have profound effects, such as antiviral therapeutics, proangiogenic agents, and regenerative medicinal applications. This study is among the first to focus on using thymosin β4 protein-derived metabolites to pioneer novel applications for peptide metabolites in biomaterials. This study found that the novel peptide metabolite acetyl-thymosin β4 (amino acid 1-17) (Ac-Tβ

Indexed as

Ac-Tβ1-17 peptideAntiviral peptidePeptide-based biomaterialPeptide metabolitesRegenerative medicineThymosin β4

Identifiers

PMID40177110
PMCPMC11964602

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.