Evidence map›Paper›PMID 40176919›Full record

ArticleACS applied optical materials2025

Modular Nanoparticle Platform for Solution-Phase Optical Sensing of Protein-Protein Interactions.

Jieying Zhou, Korneel Ridderbeek, Peijian Zou, Aaron B Naden, Stefan Gaussmann, Fangyuan Song, Pascal Falter-Braun, Euan R Kay, Michael Sattler, Jian Cui

Abstract read
In one paragraph

Article in ACS applied optical materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jieying ZhouHelmholtz Pioneer Campus, Helmholtz Munich, Neuherberg 85764, Germany.
Korneel RidderbeekHelmholtz Pioneer Campus, Helmholtz Munich, Neuherberg 85764, Germany.
Peijian ZouInstitute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Neuherberg 85764, Germany.ORCID https://orcid.org/0000-0002-7561-8310
Aaron B NadenEaStCHEM School of Chemistry, University of St. Andrews, St. Andrews KY16 9ST, U.K.
Stefan GaussmannInstitute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Neuherberg 85764, Germany.
Fangyuan SongHelmholtz Pioneer Campus, Helmholtz Munich, Neuherberg 85764, Germany.
Pascal Falter-BraunInstitute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Munich, Neuherberg 85764 Germany.ORCID https://orcid.org/0000-0003-2012-6746
Euan R KayEaStCHEM School of Chemistry, University of St. Andrews, St. Andrews KY16 9ST, U.K.ORCID https://orcid.org/0000-0001-8177-6393
Michael SattlerInstitute of Structural Biology, Molecular Targets and Therapeutics Center, Helmholtz Munich, Neuherberg 85764, Germany.
Jian CuiHelmholtz Pioneer Campus, Helmholtz Munich, Neuherberg 85764, Germany.ORCID https://orcid.org/0000-0002-2394-3357

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein-protein interactions regulate essentially all cellular processes. Understanding these interactions, including the quantification of binding parameters, is crucial for unraveling the molecular mechanisms underlying cellular pathways and, ultimately, their roles in cellular physiology and pathology. Current methods for measuring protein-protein interactions

Identifiers

PMID40176919
PMCPMC11959585

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.