Evidence map›Paper›PMID 40176854›Full record

ArticleIJID regions2025

Operationalizing SARS-CoV-2 wastewater monitoring to assess traveler health in Las Vegas, Nevada, USA.

Casey A Barber, Ching-Lan Chang, Michael A Moshi, Shahraiz Akbar, Van Vo, Edwin C Oh, Daniel Gerrity

Abstract read
In one paragraph

Article in IJID regions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Casey A BarberApplied Research and Development Center, Southern Nevada Water Authority, Las Vegas, NV, USA.
Ching-Lan ChangLaboratory of Neurogenetics and Precision Medicine, College of Sciences, University of Nevada, Las Vegas, NV, USA.
Michael A MoshiLaboratory of Neurogenetics and Precision Medicine, College of Sciences, University of Nevada, Las Vegas, NV, USA.
Shahraiz AkbarLaboratory of Neurogenetics and Precision Medicine, College of Sciences, University of Nevada, Las Vegas, NV, USA.
Van VoLaboratory of Neurogenetics and Precision Medicine, College of Sciences, University of Nevada, Las Vegas, NV, USA.
Edwin C OhLaboratory of Neurogenetics and Precision Medicine, College of Sciences, University of Nevada, Las Vegas, NV, USA.
Daniel GerrityApplied Research and Development Center, Southern Nevada Water Authority, Las Vegas, NV, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study explored expanded traveler- and tourism-focused wastewater monitoring in Las Vegas, Nevada, USA to complement community SARS-CoV-2 surveillance. Methods: Wastewater samples were collected November 2023 to July 2024 from the largest community-scale wastewater treatment plant in Southern Nevada, USA (N = 112 samples) and two upstream utility access holes (i.e. manholes), isolating an international airport (N = 68 samples) and a commercial area with high-density bars and nightclubs (N = 30-33 samples). Polymerase chain reaction-based methods quantified RNA concentrations of SARS-CoV-2 and pepper mild mottle virus; whole genome sequencing characterized SARS-CoV-2 variants (N = 83 qualifying samples). Results: SARS-CoV-2 concentrations exhibited concordance between liquids- and solids-based approaches. Similar trends were observed between methods and sampling locations; however, select manhole-level findings suggested potentially divergent COVID-19 infection profiles relative to residents. Whole genome sequencing also demonstrated similarities across sampling locations, although airport samples facilitated the identification of SARS-CoV-2 variants that either failed to spread locally (EG.6, JN.1.11) or preceded detection at the wastewater treatment plant (JN.1.7, KP.3). Conclusions: These findings offer new insight into the operationalization of broader traveler- and tourism-focused wastewater monitoring, which may capture SARS-CoV-2 concentration spikes and genomic profiles in high-tourism/nightlife areas that community-scale sampling might otherwise miss.

Indexed as

COVID-19SARS-CoV-2 variantsTraveler healthWastewater-based epidemiology (WBE)Whole genome sequencing (WGS)

Identifiers

PMID40176854
PMCPMC11964744

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.