ReviewJournal of pain research2025
Enhanced Recovery After Surgery (ERAS) Protocols in Orthopaedic Surgery: Opioids or Not Opioids?
Review in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Early postoperative hypophosphatemia is an independent predictor of ileus after transforaminal lumbar interbody fusion: a multicenter retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Efficacy and safety of intrathecal adjuvants in lower limb orthopaedic surgery: a systematic review and network meta-analysis of randomised controlled trials.Journal of anesthesia, analgesia and critical care · 2026Review
- Intraoperative use of sodium oxybate to prevent postoperative delirium in older patients undergoing major orthopedic surgery.BMC medicine · 2026Article
- A Retrospective Cohort Study on The Impact of the Enhanced Recovery After Surgery with Safe Brain Initiative on Total Knee Arthroplasty Outcomes in Türkiye.Turkish journal of anaesthesiology and reanimation · 2026Article
- Precision and pitfalls: evolving role of ultrasound-guided nerve blocks in Orthopedic perioperative pathway-a perspective.Frontiers in medicine · 2026Article
- Perioperative Use of Benzodiazepines in Orthopedic Surgery: A Brief Narrative Review.Orthopedic reviews · 2026Article
- Single-port robotic-assisted radical prostatectomy: evaluating the Da Vinci SP system in minimally invasive urologic oncology.World journal of urology · 2025Review
- Article
- Nanotechnology for pain management in orthopedic surgery.World journal of orthopedics · 2025Review
- Dexmedetomidine in Spinal Anesthesia for Orthopedic Surgery: Extending Analgesia Beyond the Operating Room.Cureus · 2025Article
- A Walk to Remember: Anesthetic Management of a Supercentenarian with Hip Fracture and Review of Literature.Cureus · 2025Article
- Advancements in Total Knee Arthroplasty over the Last Two Decades.Journal of clinical medicine · 2025Review
- Postoperative multimodal pain management: a narrative review of current practices, clinical and educational gaps, and future directions.Frontiers in anesthesiology · 2025Article
- Procedure-specific pain trajectories and process quality in elective otolaryngology surgery: a single-center cohort study.Frontiers in medicine · 2025Article
- The Effect of Transcutaneous Electrical Acupuncture Stimulation on Postoperative Pain Control and Mobility in Patients Undergoing Percutaneous Endoscopic Lumbar Discectomy: Study Protocol for a Prospective Randomized Trial.Journal of pain research · 2025Article
- Effectiveness of supraclavicular nerve and upper trunk of brachial plexus (SCUT) block versus clavipectoral fascia and supraclavicular nerve block (CPFS) in mid-shaft clavicle fracture surgery - A randomized clinical trial.Journal of anaesthesiology, clinical pharmacologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enhanced Recovery After Surgery (ERAS) protocols have transformed perioperative care in orthopaedic surgery, emphasising streamlined patient pathways for improved outcomes and treatment of chronic pain. Traditionally, opiates have been pivotal in managing postoperative (PO) pain and their efficacy in providing essential relief during the recovery phase is well-established. However, the evolving landscape of perioperative care, coupled with the opioid crisis and their association with chronic pain, has prompted a re-evaluation of their role. Orthopaedic ERAS protocols emphasise a multimodal approach to pain management, advocating for a reduction in opioid reliance. Alternative analgesic strategies, such as regional nerve blocks and non-opioid medications, are integrated into these protocols. Studies comparing opiates and opioid-free analgesia in orthopaedic ERAS are limited, making it challenging to establish a standardised approach. Some evidence suggests that opioid-free strategies, in some operating settings, may lead to improved recovery outcomes, reduced PO pain, and lower opioid consumption. However, in orthopaedics, evidence is inconclusive, necessitating further exploration. This review provides an overview of the development and multifaceted nature of ERAS protocols, which encompass a holistic approach to perioperative pain management and sustained pain relief, all while aiming to reduce the risks associated with opioid use. Striking the optimal balance between pain control and patient safety remains a priority, with the need for continued exploration and refinement of clinical guidelines in orthopaedics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.