ArticleActa ophthalmologica2025
Estimating uveal melanoma volume with ellipsoid tumour models.
Article in Acta ophthalmologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Independent validation of time to treatment as a prognostic factor in uveal melanoma.BMC cancer · 2026Article
- Volumes of Choroidal Nevi on Widefield Optical Coherence Tomography Compared to Calculations Based on Ultrasound Measurements.Ophthalmology and therapy · 2026Article
- Estimating uveal melanoma volume with ellipsoid tumour models.Acta ophthalmologica · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purposeEllipsoid tumour models are used to approximate the tumour volume of uveal melanomas, as the conventionally used ultrasound does not provide a three-dimensional visualization of the tumour. However, these models are a simplification of the actual tumour geometry. The aim of this study was to determine to what extent several of these frequently used ellipsoid tumour models accurately describe uveal melanoma volume.
methodsTumours were delineated on contrast-enhanced T1-weighted MRI for 70 uveal melanoma patients. The MRI-delineated volume was compared with three ellipsoid models, which used two-dimensional measurements such as thickness and basal diameters as input: half ellipsoids with round (V
resultsStatistically significant relative differences between MRI-delineated and model volume of 53 ± 32% (V
conclusionAll tumour models result in considerable systematic overestimations of tumour volume, with large variations in overestimation between patients. Adding the perpendicular basal diameter to the model decreases this variation. Although ellipsoid tumour models have been shown to be valuable on a group level, they should be used with caution for individual patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.