ArticleANZ journal of surgery
Postoperative inflammatory responses and association with in-hospital mortality after general surgery.
Article in ANZ journal of surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Systemic Stress Biomarkers and Patient-Reported Outcomes Following Laparoscopic IPOM+ and Open Rives-Stoppa Repair for Ventral Incisional Hernia: A Prospective Non-Randomized Comparative Study.Journal of clinical medicine · 2026Article
- The revised cardiac risk index and 90-day mortality after non-cardiac surgery: a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between postoperative in-hospital mortality and inflammatory markers has not been well described. This study aimed to characterize the association between specific clinical markers of inflammation and in-hospital mortality in the early postoperative period in general surgical patients.
methodsThis study included consecutive general surgery admissions at two tertiary hospitals in South Australia over a 2-year period. Collected data included patient demographics, Charlson comorbidity index, in-hospital mortality, vital signs, and laboratory tests. In particular, temperature, neutrophil count, lymphocyte count, platelet count, albumin level, and C-reactive protein (CRP) were collected for the 48 h after surgery. Multivariable logistic regression was conducted to examine the association between clinical inflammatory markers and in-hospital mortality in the first 24 h postoperatively and 24-48 h postoperatively.
results5493 patients were included, with an average age of 52.8 (SD 19.4). 2548 (46.4%) were female, and 53 (1.0%) experienced in-hospital mortality. In the first 24 h postoperatively, temperature >38°C, neutrophil count >14 × 10
conclusionsThis is the first study to characterize the inflammatory response using specific clinical laboratory markers, and their relative association with in-hospital mortality, in the first 2 days after general surgery.
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