Evidence map›Paper›PMID 40176690›Full record

ReviewRecent patents on biotechnology2026

Renewable and Sustainable Biorefinery: A Patent Review.

Sara Aparecida Alexandre, Paulo Afonso Granjeiro, Jose Antonio da Silva, Daniel Bonoto Goncalves

Abstract readReview
PubMed Publisher
In one paragraph

Review in Recent patents on biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sara Aparecida AlexandreCampus Cento-Oeste Dona Lindu, Federal University of São João del-Rei, Divinópolis, 35.502-296, Brazil.ORCID 0000-0002-2857-7608
Paulo Afonso GranjeiroCampus Cento-Oeste Dona Lindu, Federal University of São João del-Rei, Divinópolis, 35.502-296, Brazil.ORCID 0000-0003-0322-0861
Jose Antonio da SilvaCampus Cento-Oeste Dona Lindu, Federal University of São João del-Rei, Divinópolis, 35.502-296, Brazil.ORCID 0000-0003-4813-1029
Daniel Bonoto GoncalvesDepartment of Biotechnology, Campus Dom Bosco, Federal University of São João del-Rei, São João del-Rei, 36301-160, Brazil.ORCID 0000-0002-8178-1026

Funding

Coordination for the Improvement of Higher Education Personnel - Brazil (CAPES) 001Minas Gerais Research Foundation (FAPEMIG) APQ-03806-18, APQ-03195-21
6 · The paper itself

Abstract

backgroundBiorefineries can refer to forms of fuel production through renewable biomass derivatives, using different structures of lignocellulosic material, such as lignin, hemicellulose, and cellulose. From lignin, we can produce natural binders and adhesives, among other products. With hemicellulose, we can produce emulsifiers, resins, or lubricants, for example. Using cellulose, we can produce fuels, such as ethanol and biodiesel, or even solvents. Fuels from biorefineries can replace, totally or partially, non-renewable fuels that pollute the environment, such as oil. Considering the climate emergency, we are experiencing, the tendency to reduce the availability of oil, and the negative environmental impacts caused by it, fuels obtained through the processing of renewable plant materials present themselves as a good alternative to replacing fossil fuels. Firstgeneration ethanol (1G) can be obtained by fermenting, for example, sugar cane juice. Secondgeneration (2G) ethanol can be obtained by processing lignocellulosic waste. In this process, there must be pre-treatment and hydrolysis of the biomass before the fermentation and distillation processes. Third-generation ethanol (3G) can be obtained through the fermentation of substrate present in microalgae. Fourth-generation ethanol (4G), in turn, involves the integration of production processes from other generations, increasing the efficiency of 2G and 3G processes for ethanol production.

objectiveThe objective of this study was to investigate the scenario of patent registrations filed both on the google patents platform and espacenet, which proposes the production of fuels from biorefineries, that are renewable and sustainable.

methodsAlthough there are other lignocellulosic products originating from biorefineries, we will limit ourselves to patents aimed at the production of cellulosic ethanol. The search covered patents filed in the last 5 years (2019-2023). The 10 patents from each of the 3 biotechnological areas were selected, classified as agriculture, environment, and bioprocesses/bioengineering, totaling 30 patents to be analyzed. After selecting patents through the insertion of keywords and Boolean operators, the patents were selected by reading the title, its summary, and, finally, the full document to verify which were aligned with the study.

resultsAnalysis of the documents revealed that, in most cases, China leads the way in patent applications involving the use of fuels, such as cellulosic ethanol, which are environmentally renewable and sustainable. The main strategies for the production of renewable and sustainable fuels in the context of biorefineries explore mechanisms for reusing agricultural waste, pre-treatment of residual biomass, and reuse of biorefinery waste, among other technologies.

conclusionThe future perspective is that the production of renewable and sustainable energy, such as that coming from biorefinery fuels, has solved its challenges and contributes to the growing global energy transition process. Analyzing and incorporating advances found through patent analysis into technological development provides mechanisms for better performance in the biorefinery sector. In addition to innovations, it is possible to analyze economic and environmental challenges, promoting integrated strategies that combine sustainability and commercial viability. Thus, the energy transition can be accelerated with solutions that increase the efficiency and technological innovation of biorefineries.

Indexed as

BiofuelsBiotechnologyPatents as TopicBiomassCelluloseEthanolFermentationLigninMicroalgaePolysaccharidesBiofuelsCelluloseEthanolhemicelluloseLigninlignocellulosePolysaccharidesagricultural wastecellulosic ethanollignocellulosic productsmicroalgae.Renewable fuelssustainable energy

Identifiers

PMID40176690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.