Trial reportJournal of gastroenterology and hepatology2025
The Visibility and Performance of Small Bowel Video Capsule Endoscopy With and Without Pre-Procedural Purge Preparation in the Same Patients.
Trial report in Journal of gastroenterology and hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03555058 (Comprehensive individUalized pRoactive ThErapy of Crohn's Disease Trial), which is not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comprehensive individUalized pRoactive ThErapy of Crohn's Disease Trial: The CURE-CD Trial
Who cites it
2 citing papers in PubMed.
- Multidimensional Optimization of Small Bowel Capsule Endoscopy With Transcutaneous Electrical Acustimulation: A Randomized Controlled Trial.Journal of digestive diseasesTrial
- Bowel preparation for small bowel capsule endoscopy in patients with suspected or established Crohn's disease.World journal of gastrointestinal endoscopy · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
backgroundSmall bowel (SB) video capsule endoscopy (VCE) is an established diagnostic tool for the investigation of SB pathologies. Despite clinical studies and a few meta-analyses, an area of continuing controversy is the role of pre-procedural bowel preparation.
objectivesWe compared the visibility and performance of VCE with and without purge preparation in the same patients.
designPost hoc analysis of randomized control trial.
methodsThis is a post hoc analysis of the prospective randomized CURE-CD Trial (Comprehensive individUalized pRoactive ThErapy of Crohn's Disease trial). Established Crohn's disease (CD) patients in clinical remission were enrolled and classified into two groups according to relapse risk assessment. All patients are followed up in our clinic and undergo laboratory tests every 3 months and serial VCE studies every 6 months. The first VCE is done after bowel preparation with a clear liquid diet, PEG, and laxative, whereas the subsequent VCEs, when disease is confined to SB only, are done after a day on clear liquid diet. The VCE visibility is rated (1-4 points) by a blind observer, unaware to the preparation regimen.
resultsForty patients who underwent at least two VCEs, at baseline and after 6 months were included. Visibility scores were similar in these two time points (3.15 vs. 3.10, p = 0.8). Among the low-risk patients' group (n = 16) in whom the clinical parameters (CDAI, CRP, and fecal calprotectin) have not changed significantly during this period, Inflammatory scores assessed by the capsule Lewis score (LS) and PillCam-CD score (PCDS) were similar (median LS 225 vs. 225, p = 0.87, median PCDS 4 vs. 2, p = 0.37).
conclusionThe visibility and performance of SB VCE for monitoring Crohn's disease is not significantly influenced by purge preparation.
trial registrationClinicatrials.gov identifier: NCT03555058.
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