ArticleThe Journal of infectious diseases2025
Antenatal Respiratory Syncytial Virus and Human Metapneumovirus Illness Rates Among Pregnant Women in Thailand and the Association Between Antenatal Respiratory Syncytial Virus and Perinatal Outcomes: A Prospective Cohort Study.
Article in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07257952 (An Observational Study on the Risk of Adverse Maternal and Infant Outcomes Associated With Respiratory Viral Infections Before and During Early Pregnancy), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Observational Study on the Risk of Adverse Maternal and Infant Outcomes Associated With Respiratory Viral Infections Before and During Early Pregnancy
Who cites it
1 citing paper in PubMed.
- Human metapneumovirus infection in pregnancy: A systematic review of cohort studies and case reports.World journal of virology · 2026Article
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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
backgroundWe estimated respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) illness incidences among pregnant women and examined the association between antenatal RSV illness and preterm birth and small-for-gestational-age (SGA) infant.
methodsPregnant women aged ≥18 years were contacted twice weekly until the end of pregnancy to identify illness episodes with ≥1 of the following: myalgia, cough, runny nose/nasal congestion, sore throat, or difficulty breathing. Midturbinate nasal swabs were collected and tested for RSV and hMPV by real-time reverse transcription polymerase chain reaction. Incidences were calculated. Cox proportional hazards regression was used to estimate hazard ratios (HRs) comparing participants with and without RSV illnesses for preterm birth (live birth before 37 weeks' gestation) and SGA infant.
resultsAmong 2764 participants, the median age was 29 years (IQR, 24-34), and the median enrollment gestational age was 10 weeks (IQR, 7-14). Overall, 71 (3%) and 29 (1%) cases of RSV and hMPV illnesses were identified, respectively. Among these, 30 (42%) and 10 (34%) participants sought medical care. Incidence rates per 10 000 pregnant woman-months were 57 (95% CI, 44-72) for RSV illnesses and 23 (95% CI, 16-33) for hMPV illnesses. Antenatal RSV illness in the third trimester conferred an increased risk of preterm birth (adjusted HR, 2.50; 95% CI, 1.04-6.00) but not SGA infant (adjusted HR, 0.79; 95% CI, .29-2.16).
conclusionsAntenatal RSV illness was associated with some adverse antenatal outcomes. Pregnant women had a 0.4%-0.7% risk of RSV illness per pregnancy month, of which one-third resulted in medical visits.
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