Evidence map›Paper›PMID 40176394›Full record

ArticleThoracic cancer2025

Metastasis of Small Cell Lung Cancer to the External Auditory Canal: A Case Report.

Toshiyuki Ito, Masamichi Yoshida, Hiroto Miki, Hiroki Goto, Shuuji Kodama, Atsushi Fujiwara, Hajime Fujimoto, Tetsu Kobayashi

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Thoracic cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Toshiyuki ItoDepartment of Pulmonary and Critical Care Medicine, Mie University Faculty and Graduate School of Medicine, Tsu, Mie, Japan.ORCID https://orcid.org/0000-0001-5931-1813
Masamichi YoshidaDepartment of Respiratory Medicine, Mie Prefectural General Medical Center, Yokkaichi, Mie, Japan.
Hiroto MikiDepartment of Respiratory Medicine, Mie Prefectural General Medical Center, Yokkaichi, Mie, Japan.
Hiroki GotoDepartment of Respiratory Medicine, Mie Prefectural General Medical Center, Yokkaichi, Mie, Japan.
Shuuji KodamaDepartment of Respiratory Medicine, Mie Prefectural General Medical Center, Yokkaichi, Mie, Japan.
Atsushi FujiwaraDepartment of Respiratory Medicine, Mie Prefectural General Medical Center, Yokkaichi, Mie, Japan.
Hajime FujimotoDepartment of Pulmonary and Critical Care Medicine, Mie University Faculty and Graduate School of Medicine, Tsu, Mie, Japan.
Tetsu KobayashiDepartment of Pulmonary and Critical Care Medicine, Mie University Faculty and Graduate School of Medicine, Tsu, Mie, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with lung cancer often develop distant metastases; however, metastasis to the external auditory canal is rare. We report the case of a 77-year-old man who presented with left-sided hearing loss, otalgia, and a red mass in the left external auditory canal. Computed tomography revealed masses in the left external auditory canal, lung, and pancreas. Histopathological analysis confirmed small cell lung cancer, with thyroid transcription factor 1 positivity in multiple lesions, suggesting a primary tumor in lung. Treatment with carboplatin and etoposide led to a reduction in metastatic lesions, including those in the external auditory canal, and improved hearing impairment. This case highlights a rare instance in which chemotherapy improved ear symptoms in a patient with small cell lung cancer metastasis to the external auditory. Written informed consent was obtained from the patient for the publication of this case report and accompanying images.

Indexed as

Ear CanalEar NeoplasmsLung NeoplasmsSmall Cell Lung CarcinomaAgedCarboplatinHumansMaleTomography, X-Ray ComputedCarboplatinexternal auditory canalrare metastasissmall cell lung cancer

Identifiers

PMID40176394
PMCPMC11965702

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.