Evidence map›Paper›PMID 40176185›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2025

Deep learning-based reconstruction and superresolution for MR-guided thermal ablation of malignant liver lesions.

Moritz T Winkelmann, Jens Kübler, Sebastian Gassenmaier, Dominik M Nickel, Antonia Ashkar, Konstantin Nikolaou, Saif Afat, Rüdiger Hoffmann

Abstract read
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Moritz T WinkelmannDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany. moritz.winkelmann@med.uni-tuebingen.de.
Jens KüblerDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.
Sebastian GassenmaierDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.
Dominik M NickelMR Application Predevelopment, Siemens Healthcare AG, Forchheim, Germany.
Antonia AshkarDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.
Konstantin NikolaouDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.
Saif AfatDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.
Rüdiger HoffmannDepartment of Diagnostic and Interventional Radiology, University Hospital of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study evaluates the impact of deep learning-enhanced T1-weighted VIBE sequences (DL-VIBE) on image quality and procedural parameters during MR-guided thermoablation of liver malignancies, compared to standard VIBE (SD-VIBE).

methodsBetween September 2021 and February 2023, 34 patients (mean age: 65.4 years; 13 women) underwent MR-guided microwave ablation on a 1.5 T scanner. Intraprocedural SD-VIBE sequences were retrospectively processed with a deep learning algorithm (DL-VIBE) to reduce noise and enhance sharpness. Two interventional radiologists independently assessed image quality, noise, artifacts, sharpness, diagnostic confidence, and procedural parameters using a 5-point Likert scale. Interrater agreement was analyzed, and noise maps were created to assess signal-to-noise ratio improvements.

resultsDL-VIBE significantly improved image quality, reduced artifacts and noise, and enhanced sharpness of liver contours and portal vein branches compared to SD-VIBE (p < 0.01). Procedural metrics, including needle tip detectability, confidence in needle positioning, and ablation zone assessment, were significantly better with DL-VIBE (p < 0.01). Interrater agreement was high (Cohen κ = 0.86). Reconstruction times for DL-VIBE were 3 s for k-space reconstruction and 1 s for superresolution processing. Simulated acquisition modifications reduced breath-hold duration by approximately 2 s.

conclusionDL-VIBE enhances image quality during MR-guided thermal ablation while improving efficiency through reduced processing and acquisition times.

Indexed as

Ablation TechniquesDeep LearningLiver NeoplasmsMagnetic Resonance ImagingMagnetic Resonance Imaging, InterventionalAgedFemaleHumansLiverMaleMicrowavesMiddle AgedRetrospective Studies

Identifiers

PMID40176185
PMCPMC11966842

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.