Evidence map›Paper›PMID 40176139›Full record

ArticleInternational breastfeeding journal2025

Comparison of infant feeding practices by maternal HIV status, and associated factors, in a rural district, South Africa 2019.

Victoria Temwanani Mukhula, Moleen Zunza, Thandiwe Elsie Mbira, Vundli Ramokolo, Andrew J Prendergast, Thorkild Tylleskär, Phillippe Van de Perre, Ameena Ebrahim Goga, Nobubelo K Ngandu

Abstract readComparative Study
In one paragraph

Article in International breastfeeding journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Victoria Temwanani MukhulaDivision of Epidemiology and Biostatistics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Moleen ZunzaDivision of Epidemiology and Biostatistics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Thandiwe Elsie MbiraHIV and other Infectious Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
Vundli RamokoloHIV and other Infectious Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
Andrew J PrendergastBlizard Institute, Queen Mary University of London, London, UK.
Thorkild TylleskärCentre for International Health, Dept of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Phillippe Van de PerrePathogenesis and Control of Chronic and Emerging Infections, Montpellier University, INSERM, EFS, CHU Montpellier, Montpellier, France.
Ameena Ebrahim GogaHIV and other Infectious Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
Nobubelo K NganduHIV and other Infectious Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa. Nobubelo.Ngandu@mrc.ac.za.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of exclusive breastfeeding (EBF) during the first 6 months and breastfeeding up to 24 months in all mothers, regardless of HIV status, in high HIV prevalence settings of South Africa is not frequently evaluated. This study aimed to describe practices of EBF and breastfeeding beyond 12 months, compare these between HIV exposed (HE(s)) and unexposed infants (HU(s)), and determine associated factors.

methodsA secondary objective analysis of data from a cross-sectional study conducted during September-December-2019 in a rural South African district, was performed. Mothers living with HIV (MLHIV) paired with their infants in the following age groups: 0 to 3, > 3 to 6, > 6 to 12, and > 12 to 24 months; and mother-infant pairs without HIV with infants aged > 3 to 6 months and > 12 to 24 months, were enrolled. Descriptive statistics and bivariate and multivariable binomial regression were used for analyses.

resultsA total of 771 mother-infant pairs, 62% being MLHIV, were enrolled. Among HEs (including 10 living with HIV), the prevalence of EBF was 41.0% and 16.7% in 0-3, and, 3-6 months age-groups, respectively, and breastfeeding prevalence was 19% in 12-24 months age-group. Among HUs, the prevalence of EBF was 7.9% among 3-6 months old and breastfeeding prevalence was 38.0% among > 12-24 months old. Overall, 79.8% and 45.5% HUs and HEs aged 3-6 months were still breastfeeding, respectively. HEs were more likely to exclusively breastfeed at 3-6 months age compared to HUs (adjusted prevalence ratio [aPR] 3.84; 95% confidence interval (CI) 1.55, 9.53). Breastfeeding practice at 12-24 months age was significantly less likely among HEs (versus HUs) and in infants with unmarried/non-cohabiting mothers (versus married/co-habiting) (aPR 0.42; 95% CI 0.27, 0.63 and aPR 0.66; 95% CI 0.47, 0.92), respectively). Among HEs, breastfeeding beyond 6 months was more likely among MLHIV with known HIV-negative male partners (versus known HIV concordant relationships).

conclusionIn this study population, EBF was comparably more likely among HEs while breastfeeding beyond 12 months was more likely among HUs. Maternal marital status, frequency of antenatal care attendance and male partner's HIV status also influenced breastfeeding practice. Overall, there is still room for improvement regardless of infant HIV status, requiring continued client-sensitive strengthening of the implementation of the recommended breastfeeding practices.

Indexed as

Breast FeedingHIV InfectionsMothersAdultCross-Sectional StudiesFemaleHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalMalePrevalenceRural PopulationSouth AfricaYoung AdultBreastfeeding beyond 12 monthsExclusive breastfeedingHIV exposed infantsInfant feeding practiceVertical HIV transmission

Identifiers

PMID40176139
PMCPMC11963339

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.