Evidence map›Paper›PMID 40176107›Full record

Trial reportSubstance abuse treatment, prevention, and policy2025

Barriers and facilitators to scaling up medications for opioid use disorder in Kentucky: qualitative perspectives of treatment organization staff.

Hannah K Knudsen, Shaquita Andrews-Higgins, Sandra Back-Haddix, Michelle R Lofwall, Laura Fanucchi, Sharon L Walsh

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Substance abuse treatment, prevention, and policy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04111939 (HEALing Communities Study), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04111939 nacompletednot on this map

HEALing Communities Study: Developing and Testing an Integrated Approach to Address the Opioid Crisis

TypeinterventionalSponsorRTI InternationalRan2019 to 2025Enrolled67ConditionsOpioid Use Disorder (OUD)ArmsCommunities That HEAL, Wait-list control
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Hannah K KnudsenDepartment of Behavioral Science and Center on Drug & Alcohol Research, University of Kentucky, 845 Angliana Avenue, Room 204, Lexington, KY, 40508, USA. hannah.knudsen@uky.edu.
Shaquita Andrews-HigginsSubstance Use Research Priority Area, University of Kentucky, 845 Angliana Avenue, Lexington, KY, 40508, USA.
Sandra Back-HaddixSubstance Use Research Priority Area, University of Kentucky, 845 Angliana Avenue, Lexington, KY, 40508, USA.
Michelle R LofwallDepartment of Behavioral Science and Center on Drug & Alcohol Research, University of Kentucky, Lexington, KY, 40508, USA.
Laura FanucchiDepartment of Internal Medicine, University of Kentucky, 300 Rose St., Suite C300, Lexington, KY, 40536, USA.
Sharon L WalshDepartment of Behavioral Science and Center on Drug & Alcohol Research, University of Kentucky, Lexington, KY, 40508, USA.

Funding

Kentucky CAN HEAL (Communities and Networks Helping End Addiction Long-term)UM1DA049406 · NIDA · UNIVERSITY OF KENTUCKY · PI WALSH, SHARON L. · 2019 to 2022
$81.7M
National Institutes of Health and the Substance Abuse and Mental Health Services Administration UM1DA049406NIDA NIH HHS UM1 DA049406
6 · The paper itself

Abstract

backgroundUnderutilization of medications for opioid use disorder (MOUD) remains a persistent obstacle to addressing the opioid epidemic. This study explores MOUD agency experiences with patient census growth as well as multi-level barriers and facilitators to expanding MOUD from the perspectives of agency staff.

methodsSemi-structured qualitative interviews were conducted with 66 employees representing 30 MOUD agencies in eight Kentucky counties in the United States from December 2022 to June 2023 as part of the HEALing (Helping to End Addiction Long-term®) Communities Study in Kentucky (HCS-KY). Interviews were conducted prior to the development of partnerships to implement strategies focused on expanding MOUD census and increasing MOUD retention. Facility administrators/directors, prescribers, and clinicians were prioritized for recruitment, but agencies could identify other staff to participate. Interviews were recorded and transcribed. A consensus-based approach to coding and thematic analysis was used.

resultsAlthough some agencies had a fairly static number of patients, most described recent experiences with modest growth in MOUD census and the ability to provide same day/next day MOUD. Multi-level factors, including organizational, patient, and community factors, were perceived to impact MOUD census. Organizational characteristics impacting growth included the physical space of the clinic and staffing. Organizational policies in some agencies constrained treatment retention, while other agencies implemented innovations to better meet patients' needs. Patients often encountered numerous obstacles to treatment initiation and retention, including limited access to transportation, technology, stable housing, and childcare. These patient-level barriers often reflected community characteristics, while community stigma also impeded MOUD growth.

conclusionsAlthough some degree of growth in MOUD has occurred, multiple barriers are impeding further increases in treatment initiation and retention. Overcoming some barriers would likely require policy changes related to financing and regulation, while other barriers would require community-level efforts to decrease stigma and greater community investment in infrastructure, such as transportation and housing.

trial registrationClinicalTrials.gov, NCT04111939. Registered 30 September 2019, https://clinicaltrials.gov/ct2/show/NCT04111939 .

Indexed as

Attitude of Health PersonnelHealth Services AccessibilityOpiate Substitution TreatmentOpioid-Related DisordersFemaleHumansKentuckyMaleQualitative ResearchCommunity resourcesMedication for opioid use disorderPolicyStaffingStigmaTreatment retention

Identifiers

PMID40176107
PMCPMC11963284

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.