Evidence map›Paper›PMID 40176026›Full record

ArticleRespiratory research2025

Body composition, maximal fitness, and submaximal exercise function in people with interstitial lung disease.

Owen W Tomlinson, Anna Duckworth, Laura Markham, Rebecca L Wollerton, Michael Gibbons, Chris J Scotton, Craig A Williams

Abstract read
In one paragraph

Article in Respiratory research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Owen W TomlinsonDepartment of Public Health and Sport Science, Faculty of Health and Life Science, University of Exeter, Heavitree Road, Exeter, EX1 2LU, UK.
Anna DuckworthAcademic Department of Respiratory Medicine, Royal Devon University Hospitals NHS Foundation Trust, Barrack Road, Exeter, EX2 5DW, UK.
Laura MarkhamAcademic Department of Respiratory Medicine, Royal Devon University Hospitals NHS Foundation Trust, Barrack Road, Exeter, EX2 5DW, UK.
Rebecca L WollertonAcademic Department of Respiratory Medicine, Royal Devon University Hospitals NHS Foundation Trust, Barrack Road, Exeter, EX2 5DW, UK.
Michael GibbonsAcademic Department of Respiratory Medicine, Royal Devon University Hospitals NHS Foundation Trust, Barrack Road, Exeter, EX2 5DW, UK.
Chris J ScottonAcademic Department of Respiratory Medicine, Royal Devon University Hospitals NHS Foundation Trust, Barrack Road, Exeter, EX2 5DW, UK.
Craig A WilliamsDepartment of Public Health and Sport Science, Faculty of Health and Life Science, University of Exeter, Heavitree Road, Exeter, EX1 2LU, UK. c.a.williams@exeter.ac.uk.ORCID http://orcid.org/0000-0002-1740-6248

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiopulmonary exercise testing (CPET) is feasible, valid, reliable, and clinically useful in interstitial lung disease (ILD). However, maximal CPET values are often presented relative to body mass, whereas fat-free mass (FFM) may better reflect metabolically active muscle during exercise. Moreover, despite the value of maximal parameters, people with ILD do not always exercise maximally and therefore clinically relevant submaximal parameters must be identified. Therefore, this study assessed peak oxygen uptake (VO

methodsParticipants with ILD underwent assessment of body composition and CPET via cycle ergometry during a single study visit. To determined effectiveness of scaling for body size, both body mass and FFM were scaled using ratio-standard (X/Y) and allometric (X/Y

resultsA total of 24 participants (7 female; 69.8 ± 7.5 years; 17 with idiopathic pulmonary fibrosis) with ILD completed the study. Maximal exercise parameters did not require allometric scaling, and when scaled to FFM, it was shown that women have a significantly higher VO

conclusionThis study identified that ratio-standard scaling is sufficient in removing residual effects of body size from VO

Indexed as

Body CompositionExerciseExercise TestExercise ToleranceLung Diseases, InterstitialPhysical FitnessAgedFemaleHumansMaleMiddle AgedOxygen ConsumptionCardiopulmonary fitnessExercise testingPulmonary disease

Identifiers

PMID40176026
PMCPMC11966908

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.