Evidence map›Paper›PMID 40175996›Full record

ArticleBMC surgery2025

No differences in IVF pregnancy outcomes following hysteroscopic polypectomy using a manual hysteroscopic tissue removal device versus conventional resection.

Chen Wang, Yangqin Peng, Qinmei Wang, Yu Dong, Huimin Liu, Yaoshan Yao, Yuan Li, Ge Lin, Fei Gong, J Preston Parry and 4 more

Abstract readComparative Study
In one paragraph

Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chen Wang *Institute of Reproductive and Stem Cell Engineering, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410008, China.
Yangqin Peng *Institute of Reproductive and Stem Cell Engineering, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410008, China.
Qinmei WangClinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410221, China.
Yu DongClinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410221, China.
Huimin LiuClinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410221, China.
Yaoshan YaoClinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410221, China.
Yuan LiClinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410221, China.
Ge LinInstitute of Reproductive and Stem Cell Engineering, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410008, China.
Fei GongInstitute of Reproductive and Stem Cell Engineering, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410008, China.
J Preston ParryUniversity Mississippi Medical Center, Jackson, MS, USA.
Nigel PereiraMount Sinai Fertility, Toronto, ON, Canada.
India MorganDepartment of Obstetrics & Gynecology, Baylor Scott & White Health, Temple, TX, USA.
Steven R LindheimDepartment of Obstetrics & Gynecology, Baylor Scott & White Health, Temple, TX, USA.
Hui ChenGynecological Minimally Invasive Center, Reproductive & Genetic Hospital of Citic- Xiangya, Changsha, Hunan, China. chh1966421@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare in-vitro fertilization and embryo transfer (IVF-ET) pregnancy outcomes following endometrial polypectomy using either a manual mechanical hysteroscopic tissue resection device (mHTR) or traditional mechanical resection with scissors or polyp graspers resection.

methodsThis retrospective study examined 189 infertile patients who had undergone polypectomy prior to IVF-ET at Reproductive and Genetic Hospital of CITIC-XIANGYA. Patients undergoing polypectomy using manual mHTR resection were compared to those having the procedure through traditional mechanical resection. The primary outcome was clinical pregnancy rate (CPR) following the first ET after hysteroscopic polypectomy. Secondary outcomes included miscarriage rates and the optimal time interval from polyp resection to ET.

resultsOne-hundred eleven (58.7%) patients underwent polypectomy via manual mHTR while 78 (41.3%) patients underwent traditional mechanical resection for polypectomy. Following the first ET, the positive pregnancy rate (80.2% vs. 79.5%; p = 1.000), CPR (70.3% vs. 74.4%; p = 0.652), and MR (11.5% vs. 12.1%; p = 1.000) were similar between those undergoing mHTR and traditional mechanical resection. After stratifying by the number of menstrual cycles from procedure (after next menses; 2 to 3 menstrual cycles; and > 3 menstrual cycles later), there was no differences in CPR when comparing the time from polypectomy and resection type.

conclusionThis study suggests no differences in IVF pregnancy outcomes following hysteroscopic polypectomy regardless of surgical type using manual mHTR or traditional mechanical resection and the timing from resection.

Indexed as

Fertilization in VitroHysteroscopyInfertility, FemalePolypsPregnancy OutcomeUterine DiseasesAdultEmbryo TransferFemaleHumansPregnancyPregnancy RateRetrospective StudiesClinical pregnancy rateEndometrial polypsHysteroscopyIn-vitro fertilizationManual mechanical tissue resection deviceTraditional mechanical resection

Identifiers

PMID40175996
PMCPMC11963464

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.