ArticleBMC psychiatry2025
The mediating effects of coping strategies between symptom clusters and quality of life in lung cancer patients undergoing immunotherapy.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pre-treatment quality of life and survival outcomes in lung cancer patients: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Associations Between Cancer-Related Self-Efficacy, Coping Styles, and Perceived Stress in Patients with Lung Cancer: A Cross-Sectional Mediation Analysis.Journal of clinical medicine · 2026Article
- Organization of coping strategies and their proximal associations with pain intensity in spinal pain patients.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Coping styles mediate the association between sense of coherence and symptom distress in patients with colorectal cancer undergoing chemotherapy: A cross-sectional study.Asia-Pacific journal of oncology nursing · 2025Article
- The mediating role of medical coping modes between anxiety and fear of progression in patients with cervical intraepithelial neoplasia grade 3: a cross-sectional survey.BMC psychology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
objectiveImmunotherapy has significantly improved the survival rates of lung cancer patients. However, prevalent adverse immune reactions associated with this treatment can detrimentally affect their quality of life. Coping strategies play a crucial role throughout the cancer treatment process. Consequently, this study hypothesised that coping strategies act as a mediating factor between symptom clusters and quality of life. This study intended to provide a theoretical foundation and empirical data to support the optimisation of coping strategies for lung cancer patients, thereby enhancing their overall quality of life.
methodThis study consisted of a cross-sectional survey. Data were collected using the Memorial Symptom Assessment Scale, the Medical Coping Modes Questionnaire, the Quality of Life Questionnaire-Lung Cancer 43, and a self-designed General Information Evaluation Form. The data were fitted, and the model was refined using the maximum likelihood estimation method. Additionally, the Bootstrap method was employed to assess mediating effects.
resultsIn total, 240 participants completed the survey. During immunotherapy, lung cancer patients predominantly adopted the acceptance-resignation coping strategy, which served as a mediating factor between symptom clusters and quality of life. In contrast, the mediating effects of confrontation and avoidance coping strategies between symptom clusters and quality of life were not significant.
conclusionBoth symptom clusters and the acceptance-resignation coping strategy negatively impacted quality of life, with acceptance-resignation serving as a mediating factor between symptom clusters and quality of life. Future research should focus on developing interventions for cognitive behaviour to improve coping strategies and quality of life throughout the disease trajectory.
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