Evidence map›Paper›PMID 40175906›Full record

SynthesisBMC gastroenterology2025

The prevalence of Barrett 's esophagus in Iranian patients with gastrointestinal symptoms: a systematic review and meta-analysis.

Maryam Rashidian, Fatemeh Bastan, Hedieh Soltani, Reza Ghosheni, Kiyarash Bakhshande, Mahdi Mohammaditabar, Yasin Tabatabaei Mehr, Khaled Rahmani, Mahmood Bakhtiyari, Mostafa Qorbani and 3 more

Erratum issuedAbstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Maryam RashidianStudent Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Fatemeh BastanStudent Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Hedieh SoltaniStudent Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Reza GhosheniStudent Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Kiyarash BakhshandeStudent Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Mahdi MohammaditabarStudent Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Yasin Tabatabaei MehrStudent Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Khaled RahmaniLiver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Mahmood BakhtiyariNon-Communicable Diseases Research Center, Alborz University of Medical Sciences, Golshahr, Karaj, 31987-64653, Iran.
Mostafa QorbaniNon-Communicable Diseases Research Center, Alborz University of Medical Sciences, Golshahr, Karaj, 31987-64653, Iran.
Mojgan ForootanResearch Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mahsa MohammadiNon-Communicable Diseases Research Center, Alborz University of Medical Sciences, Golshahr, Karaj, 31987-64653, Iran.
Mohsen RajabniaNon-Communicable Diseases Research Center, Alborz University of Medical Sciences, Golshahr, Karaj, 31987-64653, Iran. dr.rajabnia@outlook.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBarrett's esophagus (BE) is a premalignant columnar metaplasia of the esophagus that predisposes victims to esophageal adenocarcinoma (EAC). Depending on differences in the study population and risk factors, the prevalence of BE may vary, from 0.4 to 20% globally. The current study aimed to systematically review and analyse the prevalence of BE in in patients with gastrointestinal symptoms in Iran. Furthermore, gastrointestinal malignancies are among the most common tumours in Iran, making this study even more significant.

methodsA systematic search was carried out in PubMed, Web of Science, Scopus, and EMBASE as well as some domestic databases including SID, Magiran, IranDoc, IranMedex from inception to the end of 2023. We included all cross-sectional studies which reported the prevalence of BE and calculated pooled prevalence.

resultsThe results of the analysis, including 9 studies in a total of 4978 cases (213 Barret diagnoses), revealed that by the results of these studies, the prevalence of Barret's esophagus is 4.4% [I2 = 94.9% [92.2%; 96.6%]/p-value < 0.0001]. Subgroup analysis, divided by region and year, revealed significant differences between groups.

conclusionsThe epidemiology of BE in Iran is not completely identified. This is the first systematic review and meta-analysis evaluating the prevalence and of BE in Iran. Due to the importance of BE in progressing to esophageal adenocarcinoma, much importance should be given to its timely diagnosis. It is strongly recommended to conduct more comprehensive studies including more patients in this field.

Indexed as

Barrett EsophagusAdenocarcinomaCross-Sectional StudiesEsophageal NeoplasmsHumansIranPrevalenceRisk FactorsBarrett’s esophagusColumnar metaplasiaIranPrevalenceSystematic review

Identifiers

PMID40175906
PMCPMC11966864

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.