Evidence map›Paper›PMID 40175888›Full record

ArticleBMC nephrology2025

Measuring bone metabolic activity in dialysis patients with renal osteodystrophy using [

Louise Aaltonen, Niina Koivuviita, Marko Seppänen, Vesa Oikonen, Anna K Kirjavainen, Heikki Kröger, Eliisa Löyttyniemi, Kaj Metsärinne

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Louise AaltonenKidney Center, Department of Medicine, Turku University Hospital, PL 52, Kiinamyllynkatu 4-8, Turku, 20521, Finland. louise.aaltonen@tyks.fi.ORCID 0000-0001-6537-9056
Niina KoivuviitaKidney Center, Department of Medicine, Turku University Hospital, PL 52, Kiinamyllynkatu 4-8, Turku, 20521, Finland.
Marko SeppänenTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku, 20521, Finland.
Vesa OikonenTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku, 20521, Finland.
Anna K KirjavainenRadiopharmaceutical Chemistry Laboratory, Turku PET Centre, University of Turku, Turku, Finland.
Heikki KrögerKuopio University Hospital and University of Eastern Finland, Kuopio, Finland.
Eliisa LöyttyniemiDepartment of Biostatistics, University of Turku, Kiinamyllynkatu 10, Turku, 20014, Finland.
Kaj MetsärinneKidney Center, Department of Medicine, Turku University Hospital, PL 52, Kiinamyllynkatu 4-8, Turku, 20521, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDynamic [

methodsTwenty-eight patients on maintenance dialysis with confirmed renal osteodystrophy underwent a dynamic [

resultsSUV measured in the lumbar spine (L1-L4) and at the AIC did not correlate with histomorphometric parameters obtained by bone biopsy. There was no statistically significant difference between SUV in different turnover groups. When adjusting the mean bone uptake of fluoride in the lumbar spine, there was a strong correlation with the blood clearance of tracer to bone (K

conclusionsThese results suggest that measurements of tracer activity in the blood 48-60 min after tracer injection could be used to correct SUVs from static [

Indexed as

Bone and BonesChronic Kidney Disease-Mineral and Bone DisorderPositron-Emission TomographyRenal DialysisSodium FluorideAdultAgedFemaleFluorine RadioisotopesHumansLumbar VertebraeMaleMiddle AgedRadiopharmaceuticalsFluorine-18Fluorine RadioisotopesRadiopharmaceuticalsSodium Fluoride[18F]NaF PET[18F]-sodium fluoride positron emission tomographyBone histomorphometryDynamicRenal osteodystrophyStatic

Identifiers

PMID40175888
PMCPMC11963257

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.