Evidence map›Paper›PMID 40175868›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

DNA Origami Multicolor Quantum Dot Platforms for Sub-diffraction Spectral Separation Imaging.

Da Huang, Lucy Haddad, Fahmida Rahman, Andrei Sapelkin, Matteo Palma

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Da HuangDepartment of Chemistry, Queen Mary University of London, London, UK.
Lucy HaddadDepartment of Physics and Astronomy, Queen Mary University of London, London, UK.
Fahmida RahmanDepartment of Physics and Astronomy, Queen Mary University of London, London, UK.
Andrei SapelkinDepartment of Physics and Astronomy, Queen Mary University of London, London, UK.
Matteo PalmaDepartment of Chemistry, Queen Mary University of London, London, UK. m.palma@qmul.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Super-resolution optical imaging techniques rely on validation standards. In this regard, it is of paramount importance to develop consistent and reliable well-defined reference samples. In this study, we employ a DNA origami scaffold to engineer a multicolor quantum dot hybrid nanostructure, and evaluate it through a recently proposed quantum dot-based spectral separation technique. Our findings underscore the utility of multivalent DNA structures, which serve as a robust and precise scaffold for the nanoscale placement of quantum dots. The employed spectral resolution method offers a straightforward and rapid means of imaging acquisition, compatible with standard confocal or fluorescence microscopes possessing spectral signal separation capabilities and a single excitation laser wavelength. This combined methodology represents a promising avenue for advancing super-resolution optical imaging techniques.

Indexed as

DNAOptical ImagingQuantum DotsMicroscopy, FluorescenceNanostructuresNucleic Acid ConformationDNADNA origamiQuantum dotsSingle moleculeSpectral separationSub-diffractionSuper-resolution microscopy

Identifiers

PMID40175868

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.