Evidence map›Paper›PMID 40175806›Full record

ArticleAesthetic plastic surgery2025

Manual Fractional Technology with CO

Houhuang Qiu, Bingliang Wu, Fuqiang Pan, Siyuan Zhou, Liming Zhang, Xiang Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Houhuang Qiu *Department of Medical Cosmetology, Second Affiliated Hospital of Guangxi Medical University, No. 166 Daxue East Road, Nanning, 530000, Guangxi, China.
Bingliang Wu *Department of Medical Cosmetology, Second Affiliated Hospital of Guangxi Medical University, No. 166 Daxue East Road, Nanning, 530000, Guangxi, China.
Fuqiang PanDepartment of Medical Cosmetology, Second Affiliated Hospital of Guangxi Medical University, No. 166 Daxue East Road, Nanning, 530000, Guangxi, China.
Siyuan ZhouDepartment of Medical Cosmetology, Second Affiliated Hospital of Guangxi Medical University, No. 166 Daxue East Road, Nanning, 530000, Guangxi, China.
Liming ZhangDepartment of Medical Cosmetology, Second Affiliated Hospital of Guangxi Medical University, No. 166 Daxue East Road, Nanning, 530000, Guangxi, China.
Xiang ZhouDepartment of Medical Cosmetology, Second Affiliated Hospital of Guangxi Medical University, No. 166 Daxue East Road, Nanning, 530000, Guangxi, China. 1256861009@qq.com.

Funding

National Natural Science Foundation of China 81760344Specific Research Project of Guangxi for Research Bases and Talents Z20201009
6 · The paper itself

Abstract

backgroundHypertrophic scars are a common fibrotic skin disorder with a high recurrence rate. While various treatment options exist, their efficacy remains uncertain. Manual fractional technology with CO

objectiveThis study retrospectively evaluated the clinical efficacy of MFT with CO

methodsA cohort of 42 patients with 48 hypertrophic scars underwent the combination therapy thrice. Scar evaluations were conducted using the patient and observer scar assessment scale (POSAS) before treatment and one month after each session. Adverse and complication reactions were monitored, and patients were followed for 6 months post-treatment. Hypertrophic scar recurrence and patient satisfaction were assessed.

resultsThe total POSAS score significantly decreased from pre-treatment [48.00 (43.00, 53.75) VS 21.29±7.167; p<0.001]. In the subgroup analysis, treatment outcomes varied significantly by skin type, with scar quantity and genetic factors influencing remission time. The recurrence rate during the 6-month follow-up was 6.24%, with a satisfaction rate of 83.34%. No severe adverse reactions were reported.

conclusionsThe findings indicate that laser-assisted drug delivery using MFT with CO LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors   www.springer.com/00266 .

Indexed as

Cicatrix, HypertrophicFluorouracilLasers, GasTriamcinolone AcetonideAdministration, CutaneousAdolescentAdultCohort StudiesCombined Modality TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentFluorouracilTriamcinolone Acetonide5-fluorouracilHypertrophic scarLaser-assisted drug deliveryManual fractional technology with CO2 laserTriamcinolone acetonide

Identifiers

PMID40175806
PMCPMC12310901

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.