Evidence map›Paper›PMID 40175760›Full record

ArticleNeurosurgical review2025

Risk factors of postprocedure seizures following standalone middle meningeal artery embolization of chronic subdural hematomas: a bi-institutional retrospective analysis.

Felipe Ramirez-Velandia, Kasuni H Ranawaka, Aryan Wadhwa, Thomas B Fodor, Mira Salih, Emmanuel O Mensah, Tzak S Lau, Niels Pacheco-Barrios, Alejandro Enriquez-Marulanda, Imad S Khan and 3 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Felipe Ramirez-VelandiaNeurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Kasuni H RanawakaNeurosurgical Division, Dartmouth Hitchcook Medical Center, Hanover, NH, USA.
Aryan WadhwaNeurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Thomas B FodorNeurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Mira SalihNeurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Emmanuel O MensahNeurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Tzak S LauNeurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Niels Pacheco-BarriosNeurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Alejandro Enriquez-MarulandaNeurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Imad S KhanNeurosurgical Division, Dartmouth Hitchcook Medical Center, Hanover, NH, USA.
Philipp TausskyNeurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Jennifer HongNeurosurgical Division, Dartmouth Hitchcook Medical Center, Hanover, NH, USA.
Christopher S OgilvyNeurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA. cogilvy@bidmc.harvard.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeizures have been reported to arise after middle meningeal artery embolization (MMAE) for the treatment of chronic subdural hematomas (cSDH). However, the rates and factors influencing their development have been poorly established in the literature. Herein, we assess for risk factors for seizures post-MMAE.

methodsA retrospective review of patients with cSDH treated with standalone MMAE from 2017 to 2021 was conducted at two academic institutions in the United States. Seizures were documented using the definition set by the International League Against Epilepsy. Medical charts and imaging were evaluated to assess risk factors associated with postprocedure seizures.

resultsA total of 113 patients, mostly males (57.5%) with 132 cSDH, were included in this analysis. The median thickness of collections was 13.1 mm, and the midline shift was 3 mm. Seizures occurred in five patients (4.4%) and resulted in longer hospitalizations (9 vs. 4 days; p = 0.03) and in-hospital mortality (20.0% vs. 0.9%; p < 0.01). Univariate analysis demonstrated that a midline shift ≥ 5 mm (OR = 6.47; 95% CI = 1.25-33.56; p = 0.03) and a pre-procedure GCS ≤ 12 (OR = 20.33; 95% CI = 2.43-170.15; p < 0.01) were risk factors for developing seizures following MMAE.

conclusionsSeizures, although uncommon, can occur following MMAE, substantially impacting the length of hospitalization and hospital mortality, with variables such as a GCS score below 13 and a midline shift ≥ 5 mm associated with their development. The role of prophylactic AEDs post-MMAE still needs further evaluation.

Indexed as

Embolization, TherapeuticHematoma, Subdural, ChronicMeningeal ArteriesPostoperative ComplicationsSeizuresAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTreatment OutcomeAntiepileptic drugsChronic subdural hematomasEmbolizationMiddle meningeal arterySeizures

Identifiers

PMID40175760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.