ArticleNature2025
Bifidobacteria support optimal infant vaccine responses.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Nationwide cohort study reveals low bifidobacteria and distinct microbiota composition and function in Swedish newborns.Gut microbes · 2026Observational
- Early antibiotic exposure and vaccine immune responses in preterm infants: potential sex-specific differences.Gut microbes · 2026Observational
- Early microbial encounters, lasting effects: strains matter.Nature reviews. Microbiology · 2026Article
- Plasticity of the infant immune system during the perinatal period.Nature reviews. Immunology · 2026Review
- Insights into Microbiota-Vaccine Crosstalk in Humans: Mechanisms, Modulators, and Translational Horizons.Vaccines · 2026Review
- Safety, tolerability, and gastrointestinal effect of a Bifidobacterium-based synergistic synbiotic in infants and toddlers.Pediatric research · 2026Article
- Review
- Article
- Vaccine Responses in Early Age.Vaccines · 2026Review
- Early-life gut microbiome composition and rotavirus vaccine-induced IgA responses in U.S. infants: a longitudinal cohort study.EBioMedicine · 2026Article
- Harnessing mucosal immunity for protective vaccines.Nature reviews. Immunology · 2026Review
- Impact of Early-Life Antibiotic Exposure on Gut Microbiome and Vaccine Immunogenicity in Infants: A Narrative Review.Journal of clinical medicine · 2026Review
- Bifidobacterium-driven immunoglobulin A production in pediatric patients with IgA deficiency and recurrent respiratory tract infections.Microbiome · 2026Article
- Gut Microbiota and Probiotics in Influenza: A Narrative Review of Mechanisms and Emerging Evidence.Viruses · 2026Review
- Peripheral rotavirus-specific T-cell responses following monovalent oral rotavirus vaccine in infants.NPJ vaccines · 2026Article
- Metabolic modeling reveals determinants of prebiotic and probiotic treatment efficacy across multiple human intervention trials.PLoS biology · 2026Article
- Effect of perinatal ampicillin or amoxicillin/clavulanate exposure on maternal and infant gut microbiome, metabolome, and infant responses to the 20-valent pneumococcal conjugate vaccine.Gut microbes reports · 2026Article
- Gut microbiota as a regulator of vaccine efficacy: implications for personalized vaccination.Gut microbes · 2025Review
- Effect of Perinatal Ampicillin or Amoxicillin/Clavulanate Exposure on Maternal and Infant Gut Microbiome, Metabolome, and Infant Responses to the 20-valent Pneumococcal Conjugate Vaccine.bioRxiv : the preprint server for biology · 2025Article
- High-Yield Outer Membrane Vesicles Derived From Probiotics as a Nanoplatform for Precise Treatment and Prophylaxis of Pseudomonas aeruginosa Infection.Journal of extracellular vesicles · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Feargal J Ryan *Precision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.ORCID 0000-0002-1565-4598
Michelle Clarke *Women's and Children's Health Network, North Adelaide, South Australia, Australia.ORCID 0000-0001-9635-8784
Miriam A Lynn *Precision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
Saoirse C BensonPrecision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
Sonia McAlisterWesfarmers Centre for Vaccines and Infectious Diseases, The Kids Institute, Perth, Western Australia, Australia.
Lynne C GilesSchool of Public Health, The University of Adelaide, Adelaide, South Australia, Australia.
Jocelyn M ChooPrecision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
Charné RossouwPrecision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
Yan Yung NgVaccine Immunology, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
Evgeny A SemchenkoInstitute for Biomedicine and Glycomics, Griffith University, Southport, Queensland, Australia.ORCID 0000-0002-5188-7946
Alyson RichardFlinders Health and Medical Research Institute, Flinders University, Bedford Park, South Australia, Australia.
Lex E X LeongFlinders Health and Medical Research Institute, Flinders University, Bedford Park, South Australia, Australia.
Steven L TaylorPrecision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
Stephen J BlakePrecision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
Joyce I MugabushakaPrecision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.ORCID 0000-0001-8168-1976
Mary WalkerWomen's and Children's Health Network, North Adelaide, South Australia, Australia.
Steve L WesselinghPrecision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
Paul V LicciardiVaccine Immunology, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.ORCID 0000-0001-6086-6285
Kate L SeibInstitute for Biomedicine and Glycomics, Griffith University, Southport, Queensland, Australia.ORCID 0000-0002-7094-3528
Damon J TumesPrecision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.ORCID 0000-0001-5709-857X
Peter RichmondWesfarmers Centre for Vaccines and Infectious Diseases, The Kids Institute, Perth, Western Australia, Australia.ORCID 0000-0001-7562-7228
Geraint B RogersPrecision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
Helen S MarshallWomen's and Children's Health Network, North Adelaide, South Australia, Australia.
David J LynnPrecision Medicine, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia. david.lynn@sahmri.com.ORCID 0000-0003-4664-1404
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accumulating evidence indicates that antibiotic exposure may lead to impaired vaccine responses
Indexed as
Anti-Bacterial AgentsBifidobacteriumImmunogenicity, VaccinePneumococcal VaccinesAnimalsAntibodies, BacterialFecesFemaleGastrointestinal MicrobiomeGerm-Free LifeHaemophilus VaccinesHumansInfantInfant, NewbornMaleMice13-valent pneumococcal vaccineAnti-Bacterial AgentsAntibodies, BacterialHaemophilus VaccinesPneumococcal VaccinesVaccines, Conjugate
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.