Evidence map›Paper›PMID 40175497›Full record

ArticleScientific reports2025

A nomogram for neurosurgical intervention in children with mild traumatic brain injury and minor subdural hematoma under 3 years.

Yuchen Liu, Houxin Fu, Jingxuan Sun, Rongting Zhang, Yi Zhong, Tianquan Yang, Yong Han, Yongjun Xiang, Bin Yuan, Ruxuan Zhou and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Yuchen Liu *Department of Neurosurgery, Children's Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Houxin Fu *Department of Pediatric Hematology and Oncology, Children's Hospital of Soochow University, Suzhou, 215006, China.
Jingxuan SunDepartment of Neurosurgery, Children's Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Rongting ZhangDepartment of Neurosurgery, Children's Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Yi ZhongDepartment of Neurosurgery, Children's Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Tianquan YangDepartment of Neurosurgery, Children's Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Yong HanDepartment of Neurosurgery, Children's Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Yongjun XiangDepartment of Neurosurgery, Children's Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Bin YuanDepartment of Neurosurgery, Children's Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Ruxuan ZhouDepartment of Neurosurgery, Children's Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Min ChenDepartment of Neurosurgery, Children's Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Hangzhou WangDepartment of Neurosurgery, Children's Hospital of Soochow University, Suzhou, 215006, Jiangsu, China. wanghangzhoudr@126.com.

Funding

Medical New Technology Program of Suzhou City SKY2021050
6 · The paper itself

Abstract

Infants and toddlers with mild traumatic brain injury (mTBI) and minor subdural hematoma (SDH) were found to have a higher risk of requiring neurosurgical intervention (NI). However, the ability to identify patients with mTBI and minor SDH who require NI remains limited. This study aims to develop a nomogram to predict NI in these patients. A nomogram predicting NI was established using demographic, clinical, radiographic, and laboratory data from patients with mTBI and minor SDH. The least absolute shrinkage and selection operator (LASSO) regression and best subsets regression (BSR) methods were employed to identify variables and select predictive factors. A nomogram was constructed using multivariable logistic regression. The model's performance was evaluated using the area under the receiver operating characteristic curve, calibration curves, the Hosmer-Lemeshow test, and decision curve analysis. Immediate seizures, anemia, and subarachnoid space depth were identified as significant predictive factors by the BSR, leading to the development of a nomogram. The AUC for this nomogram, obtained through bootstrap validation (resampling = 500), was 0.893 (95% CI, 0.844-0.942). The model demonstrated good calibration, and decision curve analysis showed that when the threshold probability ranged from 7 to 83%, using the nomogram to predict NI provided a net benefit. A novel nomogram has been developed to accurately assess the risk of NI in children under 3 years of age with mTBI and minor SDH, potentially aiding in clinical decision-making.

Indexed as

Brain ConcussionHematoma, SubduralNeurosurgical ProceduresNomogramsChild, PreschoolFemaleHumansInfantMaleROC CurveMild traumatic brain injuryNomogramPrediction modelSubdural hematoma

Identifiers

PMID40175497
PMCPMC11965514

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.