Evidence map›Paper›PMID 40175387›Full record

ArticleNature communications2025

Photocatalytic deoxygenative Z-selective olefination of aliphatic alcohols.

Sai Rohini Narayanan Kolusu, Irene Sánchez-Sordo, Carla Aira-Rodríguez, Emanuele Azzi, Manuel Nappi

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Photolysis of COJournal of the American Chemical Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sai Rohini Narayanan KolusuCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Rúa de Jenaro de la Fuente, s/n, 15705, Santiago de Compostela, A Coruña, Spain.ORCID http://orcid.org/0000-0002-5292-8658
Irene Sánchez-SordoCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Rúa de Jenaro de la Fuente, s/n, 15705, Santiago de Compostela, A Coruña, Spain.ORCID http://orcid.org/0000-0001-7471-1831
Carla Aira-RodríguezCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Rúa de Jenaro de la Fuente, s/n, 15705, Santiago de Compostela, A Coruña, Spain.ORCID http://orcid.org/0000-0003-0763-6290
Emanuele AzziCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Rúa de Jenaro de la Fuente, s/n, 15705, Santiago de Compostela, A Coruña, Spain.ORCID http://orcid.org/0000-0002-2284-2925
Manuel NappiCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Rúa de Jenaro de la Fuente, s/n, 15705, Santiago de Compostela, A Coruña, Spain. manuel.nappi@usc.es.ORCID http://orcid.org/0000-0002-3023-0574

Funding

Ministry of Economy and Competitiveness | Agencia Estatal de Investigación (Spanish Agencia Estatal de Investigación) PID2020-113067GA-I00Ministry of Economy and Competitiveness | Agencia Estatal de Investigación (Spanish Agencia Estatal de Investigación) TED2021-129833A-I00Xunta de Galicia ED431G 2023/03Xunta de Galicia ED481A-2023-178
6 · The paper itself

Abstract

Alcohols are one of the most abundant functional groups in commercially available materials and biologically active compounds. Herein, we report a metal-free photocatalytic method for the deoxygenative Z-selective olefination of aliphatic alcohols. Key to this methodology is the radical olefination and isomerization of unstabilized open-shell species generated in situ by a catalytic reductive scission of benzoate esters. These processes are simultaneously orchestrated by a single phenothiazine photocatalyst via singlet and triplet excited states. Our protocol is distinguished by its wide substrate scope and broad applicability, even in the context of pharmaceuticals and saccharides. Given the mild and water-compatible conditions, our chemistry can also be utilized to functionalize DNA headpieces for DELs applications.

Identifiers

PMID40175387
PMCPMC11965276

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.