Evidence map›Paper›PMID 40175283›Full record

SynthesisEuropean psychiatry : the journal of the Association of European Psychiatrists2025

Prevalence of suicidal behaviour in adolescents and youth at ultra-high risk for psychosis: A systematic review and meta-analysis.

Shi Han Ang, Siddarth Venkateswaran, Mahir Bakulkumar Goda, Kuhanesan N C Naidu, Ganesh Kudva Kundadak, Mythily Subramaniam

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in European psychiatry : the journal of the Association of European Psychiatrists, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Psychiatric diagnosis on the edge: is there evidence of benefit?European child & adolescent psychiatry · 2026
    Article
  5. Real-world comprehensive care of people living with schizophrenia: recommendations across different settings and clinical stages.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shi Han AngYong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0009-0006-8052-549X
Siddarth VenkateswaranYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Mahir Bakulkumar GodaYong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0009-0009-9824-732X
Kuhanesan N C NaiduDepartment of Psychological Medicine, National University Hospital, Singapore.ORCID 0009-0007-4118-9195
Ganesh Kudva KundadakDepartment of Psychological Medicine, National University Hospital, Singapore.ORCID 0000-0001-9157-2175
Mythily SubramaniamDepartment of Psychological Medicine, National University Hospital, Singapore.ORCID 0000-0003-4530-1096

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSuicide remains a major risk factor for individuals suffering from schizophrenia and its prodromal state (i.e., Ultra-High Risk for Psychosis). However, less is known about the prevalence of suicidal behaviour among the adolescent and youth UHR population, a demographic vulnerable to the psychosocial and environmental risk factors of suicide. This review aims to synthesise existing literature on the prevalence of suicidal ideation and behaviour in the adolescent and youth at Ultra-High Risk for Psychosis (UHR), and the associations between suicidal behaviour and its correlates.

methodsThe databases PsycINFO, PubMed, Embase, Cochrane Library, Web of Science, and Scopus were accessed up to July 2024. A meta-analysis of prevalence was subsequently performed for lifetime suicidal ideation, lifetime non-suicidal self-injury, lifetime suicidal attempt, and current suicidal ideation. A narrative review was also carried out for the correlates of suicidal behaviour amongst adolescents and youth in the UHR population.

resultsStudies were included in this meta-analysis. Meta-analysis revealed a high prevalence of lifetime suicidal ideation (58%), lifetime non-suicidal self-injury (37%), lifetime suicidal attempt (25%), and current (2 week) suicidal ideation (56%). The narrative review revealed that a personal transition to psychosis and a positive family history of psychosis were associated with suicidal attempts, while depression was associated with both suicidal attempts and suicidal ideation.

conclusionThe prevalence of suicidal ideation and behaviour among UHR adolescents and youth is high and comparable to that of the general UHR population. Existing measures that mitigate suicide risk in the general UHR population should be adopted for the youth context.

Indexed as

Psychotic DisordersSelf-Injurious BehaviorSuicidal IdeationSuicide, AttemptedAdolescentHumansPrevalenceRisk Factorschild and adolescent psychiatryfirst episode psychosisschizophreniasuicideultra high risk

Identifiers

PMID40175283
PMCPMC12090029

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.