Evidence map›Paper›PMID 40175161›Full record

ArticleEarly intervention in psychiatry2025

Connection Learning Healthcare System Hub of the Early Psychosis Intervention Network: Program and Participant Characteristics.

Monica E Calkins, Megan Jumper, Arielle Ered, Fanghong Dong, Deepak K Sarpal, Krista K Baker, Donna J Bencivengo, Russell L Margolis, Robert W Buchanan, Yasmine Boumaiz and 31 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07713849 (Adapting and Improving Transition Care for First Episode Psychosis), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07713849 recruitingnot on this mapstarted 2026, after this paper: background citation

Adapting and Improving Transition Care for First Episode Psychosis

Typeobservational_patient_registrySponsorUniversity of ChicagoRan2026 to 2029Enrolled75ConditionsSchizoaffective Disorders, Bipolar Disorder With Psychotic Features, Schizophrenia Disorders, Major Depressive Disorder With Psychotic FeaturesArmsTransition Care Team
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

Monica E CalkinsNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-0546-0263
Megan JumperNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Arielle EredNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Fanghong DongNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Deepak K SarpalDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-5842-6782
Krista K BakerJohns Hopkins Bayview Medical Center, Community Psychiatry Program, Baltimore, Maryland, USA.
Donna J BencivengoNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Russell L MargolisDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Robert W BuchananMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Yasmine BoumaizDivision of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Elizabeth BurrisWesley Family Services First Episode Psychosis Program-ENGAGE, New Kensington, Pennsylvania, USA.
Philip D CampbellNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-7292-0197
K N Roy ChengappaDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Catherine ConroyNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Akinyi CookeJohns Hopkins Bayview Medical Center, Community Psychiatry Program, Baltimore, Maryland, USA.
Faith DickersonDepartment of Psychology, Sheppard Pratt, Baltimore, Maryland, USA.
Nyasia FlowersJohns Hopkins Bayview Medical Center, Community Psychiatry Program, Baltimore, Maryland, USA.
Mandy FaubleUniversity of Pittsburgh Medical Center Western Behavioral Health at Safe Harbor, Erie, Pennsylvania, USA.
Richard W GoldbergDivision of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Alexander HarvinDepartment of Psychology, Sheppard Pratt, Baltimore, Maryland, USA.
Carolyn HowellJohns Hopkins Bayview Medical Center, Community Psychiatry Program, Baltimore, Maryland, USA.
Christian KellyUniversity of Pittsburgh Medical Center, Western Psychiatric Hospital, Pittsburgh, Pennsylvania, USA.
Julie KreyenbuhlDivision of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Lan LiDivision of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Alicia LuckstedDivision of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Jill A MarstellerDepartment of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Alexander MoxamNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Denise NamowiczChildren's Services Center, Wilkes Barre, Pennsylvania, USA.
Swati NayarDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Jamie OkoDepartment of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Jessie RiggsNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0009-0008-3285-8032
Arunadevi SaravanaDivision of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Rachel ScheinbergDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
William R SmithNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-6611-0817
Richard StatesUniversity of Pittsburgh Medical Center Western Behavioral Health at Safe Harbor, Erie, Pennsylvania, USA.
Timur Suhail-SindhuDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jerome TaylorNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Crystal L VatzaNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Max WolcottJohns Hopkins Bayview Medical Center, Community Psychiatry Program, Baltimore, Maryland, USA.
Christian G KohlerNeurodevelopment and Psychosis Section, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Melanie E BennettDivision of Psychiatric Services Research, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Funding

UMB Admin CoreP01MH139228 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI MELANIE E. BENNETT · 2024 to 2026
$6.3M
Improving Engagement in Black Clients Participating in Coordinated Specialty Care: A Mixed Methods Pilot StudyR01MH120550 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI BENNETT, MELANIE E. · 2020 to 2023
$5.9M
Targeting Emotion Dysregulation to Reduce Suicide in People with PsychosisK23MH125024 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI PHALEN, PETER LEE · 2022 to 2025
$711k
NIMH NIH HHS 1R01MH120550-01A1NIMH NIH HHS K23 MH125024NIMH NIH HHS P01 MH139228NIMH NIH HHS R01 MH120550Pennsylvania Office of Mental Health and Substance Abuse Services CFDA# 93.958
6 · The paper itself

Abstract

aimConnection Learning Healthcare System, one of the eight hubs of the National Institute of Mental Health funded Early Psychosis Intervention Network, supports uniform data collection, analysis, feedback and infrastructure development to promote a culture of continuous quality improvement across 25 Coordinated Specialty Care programs serving young people experiencing first episode psychosis and their families in Maryland and Pennsylvania. This first report describes the hub and its constituent programs, the approach for developing and implementing a hub-wide core assessment battery harmonised with the national battery, and preliminary program and participant characteristics.

methodsOur hub developed and implemented a computerised core assessment battery, administered every 6 months and developed an integrated system for managing and analysing data.

resultsBetween 1 January 2021 and 27 November 2023, 1059 participants were newly admitted to a hub program. The entire cohort (N = 1381) included newly admitted participants and those already in a program as of 1 January 2021. A total of 1245 complete assessment batteries were collected across all time points from 797 participants, with an additional 1920 partially completed batteries collected from 1319 participants. Data are uploaded to the National Data Coordinating Center, where our hub is the third largest data contributor. Descriptive information on programs and participants is provided.

conclusionsAs part of our learning healthcare system to improve clinical services and outcomes across two states, we have successfully implemented a standardised, computerised core assessment battery of essential characteristics and clinical outcomes. Successes, challenges and recommendations for data collection are provided. This paper will serve as a vital methodological resource for users of the unprecedented Early Psychosis Intervention Network national research database seeking to accelerate and improve early psychosis research.

Indexed as

Early Medical InterventionLearning Health SystemMental Health ServicesPsychotic DisordersAdolescentAdultFemaleHumansMaleMarylandNational Institute of Mental Health (U.S.)PennsylvaniaUnited StatesYoung Adultcoordinated speciality careearly psychosis intervention networkEPINETfirst‐episode psychosislearning health care system

Identifiers

PMID40175161
PMCPMC11964890

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.