Evidence map›Paper›PMID 40175064›Full record

ArticleNMR in biomedicine2025

Hyperpolarized

M Kate Curtis, Jordan J McGing, Brianna J Stubbs, Vicky Ball, Lowri E Cochlin, David P O'Neill, Christoffer Laustsen, Mark A Cole, Peter A Robbins, Damian J Tyler and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NMR in biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

M Kate CurtisDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-0096-8199
Jordan J McGingOxford Centre for Clinical Magnetic Resonance Research, Oxford, UK.
Brianna J StubbsBuck Institute for Research on Aging, Novato, California, USA.
Vicky BallDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Lowri E CochlinDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
David P O'NeillDepartment of Biomedical Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, Illinois, USA.ORCID https://orcid.org/0000-0002-1609-7666
Christoffer LaustsenThe MR Research Centre, Health, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-0317-2911
Mark A ColeUniversity of Nottingham Medical School, Nottingham, UK.ORCID https://orcid.org/0000-0002-0727-7833
Peter A RobbinsDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Damian J TylerDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-0780-8905
Jack J MillerThe MR Research Centre, Health, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-6258-1299

Funding

British Heart Foundation FS/10/002/28078British Heart Foundation FS/14/17/30634British Heart Foundation RE/13/1/30181Engineering and Physical Sciences Research Council EP/J013250/1Engineering and Physical Sciences Research Council EP/M508111/1Novo Nordisk Fonden NNF21OC0068683Royal Commission for the Exhibition of 1851Vifor Pharma
6 · The paper itself

Abstract

Existing techniques for the non-invasive in vivo study of dynamic changes in skeletal muscle metabolism are subject to several limitations, for example, poor signal-to-noise ratios which result in long scan times and low temporal resolution. Hyperpolarized [1-

Indexed as

Carbon-13 Magnetic Resonance SpectroscopyLactic AcidMuscle, SkeletalPhysical Conditioning, AnimalPyruvate Dehydrogenase ComplexAnimalsCarbon IsotopesMagnetic Resonance SpectroscopyMaleMiceMice, Inbred C57BLOxidation-ReductionPyruvic AcidCarbon-13Carbon IsotopesLactic AcidPyruvate Dehydrogenase ComplexPyruvic Acid13C MRShyperpolarized 13Cmagnetic resonancemouse modelsmuscle metabolism

Identifiers

PMID40175064
PMCPMC11964792

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.