Evidence map›Paper›PMID 40174868›Full record

ArticleBrain, behavior, and immunity2025

The effects of P2Y12 loss on microglial gene expression, dynamics, and injury response in the cerebellum and cerebral cortex.

Mark B Stoessel, Rianne D Stowell, Rebecca L Lowery, Linh H D Le, Andy N Vu, Brendan S Whitelaw, Ania K Majewska

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain, behavior, and immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Mark B StoesselDepartment of Neuroscience, Delmonte Institute for Neuroscience, University of Rochester, Rochester NY 14642, USA; Neuroscience Graduate Program, University of Rochester, Rochester, NY 14642, USA. Electronic address: mark_stoessel@urmc.rochester.edu.
Rianne D StowellDepartment of Neuroscience, Delmonte Institute for Neuroscience, University of Rochester, Rochester NY 14642, USA. Electronic address: rianne_stowell@urmc.rochester.edu.
Rebecca L LoweryDepartment of Neuroscience, Delmonte Institute for Neuroscience, University of Rochester, Rochester NY 14642, USA.
Linh H D LeDepartment of Neuroscience, Delmonte Institute for Neuroscience, University of Rochester, Rochester NY 14642, USA; Neuroscience Graduate Program, University of Rochester, Rochester, NY 14642, USA. Electronic address: linh_le@urmc.rochester.edu.
Andy N VuDepartment of Neuroscience, Delmonte Institute for Neuroscience, University of Rochester, Rochester NY 14642, USA.
Brendan S WhitelawDepartment of Neuroscience, Delmonte Institute for Neuroscience, University of Rochester, Rochester NY 14642, USA; Neuroscience Graduate Program, University of Rochester, Rochester, NY 14642, USA; Medical Scientist Training Program, University of Rochester 14642, USA.
Ania K MajewskaDepartment of Neuroscience, Delmonte Institute for Neuroscience, University of Rochester, Rochester NY 14642, USA; Center for Visual Science, University of Rochester, Rochester, NY 14642, USA. Electronic address: Ania_majewska@urmc.rochester.edu.

Funding

Imaging visual plasticity in vivo.R01EY019277 · NEI · UNIVERSITY OF ROCHESTER · PI MAJEWSKA, ANNA K · 2009 to 2016
$2.6M
Dynamic neuroimmune interactions in the onset and progression of FASDR01AA027111 · NIAAA · UNIV OF ARKANSAS FOR MED SCIS · PI DREW, PAUL D, MAJEWSKA, ANNA K · 2018 to 2022
$2.3M
Mechanisms that regulate microglial dynamics in the context of plasticity (Supplement)R01NS114480 · NINDS · UNIVERSITY OF ROCHESTER · PI MAJEWSKA, ANNA K · 2020 to 2024
$2.2M
The effects of arousal on microglial motilityR21NS099973 · NINDS · UNIVERSITY OF ROCHESTER · PI MAJEWSKA, ANNA K · 2016 to 2017
$423k
The role of PI3Kg signaling in microglial dynamics and experience dependent synaptic plasticityF30MH120974 · NIMH · UNIVERSITY OF ROCHESTER · PI WHITELAW, BRENDAN STEVEN · 2019 to 2022
$198k
Adolescent plasticity of the dopaminergic mesofrontal circuit: cellular mechanisms and behavioral rolesF32MH124298 · NIMH · UNIVERSITY OF ROCHESTER · PI STOWELL, RIANNE · 2021 to 2022
$143k
Dynamics of and Function Cerebellar MicrogliaF31NS120609 · NINDS · UNIVERSITY OF ROCHESTER · PI STOESSEL, MARK BLOHM · 2020 to 2022
$138k
Noradrenergic modulation of microglial dynamics and synaptic plasticityF31NS105249 · NINDS · UNIVERSITY OF ROCHESTER · PI STOWELL, RIANNE · 2018 to 2019
$90k
NEI NIH HHS R01 EY019277NIAAA NIH HHS R01 AA027111NIMH NIH HHS F30 MH120974NIMH NIH HHS F32 MH124298NINDS NIH HHS F31 NS105249NINDS NIH HHS F31 NS120609NINDS NIH HHS R01 NS114480NINDS NIH HHS R21 NS099973
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ATPChemotaxisDelay eye blink conditioningPurinergic signalingTwo-photon imaging

Identifiers

PMID40174868
PMCPMC12239733

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.