Evidence map›Paper›PMID 40174408›Full record

ArticlePsychiatry research2025

Suicidal ideation and avoidant/restrictive food intake disorder: Findings from the ARFID-GEN study.

Baiyu Qi, Maria A Kalantzis, Laura M Thornton, Jennifer P White, Casey M MacDermod, Shelby N Ortiz, Emily M Pisetsky, Lisa Dinkler, Jerry D Guintivano, Jessica S Johnson and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychiatry research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Baiyu QiDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27516, USA.
Maria A KalantzisDepartment of Psychology, Bowling Green State University, Bowling Green, OH, 43403, USA.
Laura M ThorntonDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Jennifer P WhiteDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Casey M MacDermodDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Shelby N OrtizDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Emily M PisetskyDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Lisa DinklerDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, 171 77, Stockholm, Sweden.
Jerry D GuintivanoDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Jessica S JohnsonDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Nadia MicaliCenter for Eating and Feeding Disorders Research, Psychiatric Center Ballerup, Mental Health Services of the Capital Region of Denmark, Ballerup, Denmark; Institute of Biological Psychiatry, Psykiatrisk Center Sct. Hans, Boserupvej 2, 4000, Roskilde, Denmark; Great Ormond Street Hospital Institute of Child Health, University College London, London, UK.
Cynthia M BulikDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, 171 77, Stockholm, Sweden; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA. Electronic address: cynthia_bulik@med.unc.edu.

Funding

Genetic Architecture of Avoidant/Restrictive Food Intake DisorderR56MH129437 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M, MICALI, NADIA · 2022 to 2023
$1.5M
NIMH NIH HHS R56 MH129437
6 · The paper itself

Abstract

This study examined the prevalence of suicidal ideation (SI) among adults with avoidant/restrictive food intake disorder (ARFID) across different demographic groups and explored associations between SI and specific ARFID dimensions. The sample included 3299 adults who screened positive for ARFID using two validated scales. SI over the past two weeks was assessed using item 9 from the Patient Health Questionnaire-9. The overall prevalence of SI was 22.9 %, with a higher prevalence among transgender and gender-diverse (TGD) individuals (34.7 %) compared to cisgender men (17.8 %) and cisgender women (16.8 %). Participants with SI (mean = 27.6 years, SD = 10.1) were younger than those without SI (mean = 32.3 years, SD = 13.4). The ARFID dimensions picky eating/sensory-based avoidance and low appetite/lack of interest in eating or food were positively associated with SI; however, these associations became non-significant after adjusting for age, gender, and depression. Interestingly, fear/concern about aversive consequences was significantly negatively associated with SI after adjusting for covariates. Our results suggest that the fear presentation of ARFID may be a distinct subtype with a lower risk of suicidality compared to other presentations, highlighting the importance of comprehensively evaluating ARFID dimensions and underlying depressive symptoms to better address the risk of suicidality.

Indexed as

Avoidant Restrictive Food Intake DisorderFeeding and Eating DisordersSuicidal IdeationAdolescentAdultFemaleHumansMaleMiddle AgedPrevalenceTransgender PersonsYoung AdultEating disordersPicky eatingSelective eatingSuicidalitySuicide

Identifiers

PMID40174408
PMCPMC12671335

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.