Evidence map›Paper›PMID 40173299›Full record

ArticleAmerican journal of respiratory cell and molecular biology2025

Tartrate-Resistant Acid Phosphatase 5 (TRAP5) Promotes Eosinophil Migration During Allergic Asthma.

Médea Padra, Jesper Bergwik, Anna Adler, Genevieve Marcoux, Ravi K V Bhongir, Praveen Papareddy, Arne Egesten

Abstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Médea PadraRespiratory Medicine, Allergology, & Palliative Medicine and.ORCID 0000-0001-7089-2188
Jesper BergwikRespiratory Medicine, Allergology, & Palliative Medicine and.
Anna AdlerRespiratory Medicine, Allergology, & Palliative Medicine and.
Genevieve MarcouxRespiratory Medicine, Allergology, & Palliative Medicine and.
Ravi K V BhongirRespiratory Medicine, Allergology, & Palliative Medicine and.
Praveen PapareddyInfection Medicine, Department of Clinical Sciences Lund, Skåne University Hospital and Lund University, Lund, Sweden.
Arne EgestenRespiratory Medicine, Allergology, & Palliative Medicine and.

Funding

the Alfred Österlund Foundationthe Royal Physiographic Society of Lundthe Swedish Government Funds for Clinical Research 46402the Swedish Heart and Lung Foundation 20220193the Swedish Research Council 2023-02013
6 · The paper itself

Abstract

Allergic asthma is characterized by Type 2 inflammation and eosinophilia. Tartrate-resistant acid phosphatase 5 (TRAP5; also referred to as acid phosphatase 5 [ACP5]) is a metallophosphatase expressed by alveolar macrophages that dephosphorylates osteopontin, a phosphoglycoprotein with increased expression in asthma. To investigate the role of TRAP5 during asthma, we used a murine model of ovalbumin (OVA)-induced allergic airway inflammation as well as IL-33-induced airway inflammation, including

Indexed as

AsthmaCell MovementEosinophilsTartrate-Resistant Acid PhosphataseAnimalsCytokinesDisease Models, AnimalFemaleInflammationInterleukin-33LungMiceMice, Inbred C57BLMice, KnockoutOsteopontinOvalbuminCytokinesInterleukin-33OsteopontinOvalbuminTartrate-Resistant Acid PhosphataseasthmaeosinophilsIL-33osteopontinTRAP5/ACP5

Identifiers

PMID40173299
PMCPMC12498364

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.