Evidence map›Paper›PMID 40173283›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

Clinician Prediction of Hyperinflammatory Acute Respiratory Distress Syndrome Subphenotypes: Overestimated but Prognostic.

Georgios D Kitsios, Menaal Haque, William G Bain, Charles Dela Cruz, Bryan J McVerry, Faraaz A Shah, Acute Lung Injury Registry Investigators

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Finding the Four-Leaf CLOVERS: Biologic Subphenotypes and Fluid Tolerance in Sepsis.American journal of respiratory and critical care medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Georgios D KitsiosDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine and.ORCID 0000-0002-1018-948X
Menaal HaqueGeorge Washington University School of Medicine and Health Sciences, Washington, District of Columbia; and.
William G BainDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine and.ORCID 0000-0001-8506-0552
Charles Dela CruzDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine and.
Bryan J McVerryDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine and.
Faraaz A ShahDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine and.
Acute Lung Injury Registry Investigators

Funding

Regulation of Cardiolin Byosynthesis in Epithelial InjuryP01HL114453 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MALLAMPALLI, RAMA K · 2014 to 2023
$21.3M
Precision Medicine Approach to Glucocortisteroids in SepsisR01GM141081 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ANGUS, DEREK C, YENDE, SACHIN · 2021 to 2024
$2.6M
Intrapulmonary itaconate as a host-protective metabolite during ER Stress and Klebsiella pneumoniae infectionK08HL163324 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Tomeka L Suber · 2022 to 2026
$804k
The impact of glycocalyx degradation on ARDS pathogenesis and outcomesK23HL173662 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Alicia N Rizzo · 2025 to 2026
$377k
Precision Medicine for Nutrition in EDENR21HL168070 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHAH, FARAAZ ALI · 2023 to 2024
$239k
Microbial Determinants of Acute Respiratory Distress Syndrome Severity (MiDAS)R03HL162655 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KITSIOS, GEORGIOS · 2022 to 2023
$159k
American Lung Association COVID-19 Respiratory Virus ResearchNHLBI NIH HHS K08 HL163324NHLBI NIH HHS K23 HL173662NHLBI NIH HHS P01 HL114453NHLBI NIH HHS R03 HL162655NHLBI NIH HHS R21 HL168070NHLBI NIH HHS R21HL168070NIGMS NIH HHS R01 GM141081NIGMS NIH HHS R01GM141081
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40173283
PMCPMC12264653

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.