Evidence map›Paper›PMID 40173218›Full record

ArticleScience advances2025

Direct observation and force modulation of single-bond reactions at the ion/metal interface.

Cong Zhao, Kun Li, Jie Hao, Yanlei Wang, Hongyan He, Chuancheng Jia, Xuefeng Guo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Precise Probing of Interfaces at the Single-Molecule Scale.Nanomaterials (Basel, Switzerland) · 2026
    Review
  3. The Fantastic Single-Molecule Techniques.Chemical & biomedical imaging · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cong ZhaoCenter of Single-Molecule Sciences, Institute of Modern Optics, Frontiers Science Center for New Organic Matter, Tianjin Key Laboratory of Microscale Optical Information Science and Technology, College of Electronic Information and Optical Engineering, Nankai University, Tianjin 300350, P. R. China.ORCID 0009-0001-2250-3616
Kun LiBeijing Key Laboratory of Ionic Liquids Clean Process, State Key Laboratory of Mesoscience and Engineering, CAS Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, P. R. China.ORCID 0009-0000-4698-6459
Jie HaoBeijing National Laboratory for Molecular Sciences, National Biomedical Imaging Center, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China.
Yanlei WangDepartment of Chemistry, School of Chemistry and Life Resources, Renmin University of China, Beijing 100872, P. R. China.ORCID 0000-0002-2214-8781
Hongyan HeBeijing Key Laboratory of Ionic Liquids Clean Process, State Key Laboratory of Mesoscience and Engineering, CAS Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, P. R. China.ORCID 0000-0003-1291-2771
Chuancheng JiaCenter of Single-Molecule Sciences, Institute of Modern Optics, Frontiers Science Center for New Organic Matter, Tianjin Key Laboratory of Microscale Optical Information Science and Technology, College of Electronic Information and Optical Engineering, Nankai University, Tianjin 300350, P. R. China.ORCID 0000-0002-1513-8497
Xuefeng GuoCenter of Single-Molecule Sciences, Institute of Modern Optics, Frontiers Science Center for New Organic Matter, Tianjin Key Laboratory of Microscale Optical Information Science and Technology, College of Electronic Information and Optical Engineering, Nankai University, Tianjin 300350, P. R. China.ORCID 0000-0001-5723-8528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elucidating the mechanisms of ion-involved interfacial reactions at the single-bond level is important for understanding interface science. Here, the reaction between pyridine ions and protons at the solid-liquid interface is studied in situ using a single-molecule conductance measurement technique. By manipulating the interfacial electrostatic potential, an ion/metal interfacial state relying on electrostatic interactions has been discovered, comprising terminal group-hydrogen-gold in specific. The reversible interfacial protonation reaction mechanism is revealed in situ at the single-bond level based on this interfacial state. Experiment results also indicate that external forces can effectively regulate this ion-involved interfacial reaction. This work provides a single-bond approach for in situ investigations of ion-involved interfacial reactions with an ion/metal interfacial state, thus promoting the development of interface science.

Identifiers

PMID40173218
PMCPMC11963960

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.