SynthesisPloS one2025
Dietary phytochemical index and the risk of cancer: A systematic review and meta-analysis.
Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Dietary Phytochemical Index and Its Relationship With Diminished Ovarian Reserve: Evidence From a Case-Control Study.Endocrinology, diabetes & metabolism · 2026Observational
- Tuberculosis Preceding Lung Cancer: A Contemporary Meta-Analysis Revealing a Critical Gap in Post-2020 Evidence.Cancers · 2026Review
- Higher dietary phytochemical index is associated with lower risk of epithelial ovarian cancer in Chinese women: a case-control study.Frontiers in nutrition · 2026Article
- Dietary phytochemical index and biomarker profiles are associated with colorectal cancer odds: integrating dietary intake with blood biomarkers.Frontiers in nutrition · 2026Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecently, the association between dietary phytochemical index (DPI) and the risk of cancer has been the focus of researchers, however, this possible association has not been fully understood. The current meta-analysis aimed to assess the relationship between DPI and the risk of cancers.
methodsA literature search by the main keywords such as "dietary phytochemical index", "DPI", and "cancer" was completed using Scopus, PubMed, and Web of Science up to December 2024 and references of retrieved relevant articles. Observational studies examining the association between the DPI and the risk of cancers were included. The reported odds ratio (OR) with a 95% confidence interval (CI) for each study was converted into log OR, and their standard deviation was calculated. Then to compute the pooled OR, the random-effects model with inverse variance weighting method was performed.
resultsNine case-control studies were included in the present meta-analysis. The sample size ranged from 120 to 851 with an age range from 18 to 75 years. The pooled results indicate an inverse association between DPI and the risk of all cancers (OR: 0.40; 95% CI: 0.29-0.54, I2 = 0.00%; P-value < 0.001). Also, subgroup analysis indicated that higher a DPI score is related to the decreased risk of breast cancer (OR: 0.38; 95% CI: 0.26-0.55, I2 = 0.00%; P-value < 0.001) and pooled non-breast cancer including glioma, prostate, and colorectal cancers (OR: 0.43; 95% CI: 0.27-0.71, I2 = 0.00%; P-value = 0.001).
conclusionsThe results of the current meta-analysis revealed that the higher DPI score is associated with a decreased odds of cancers. Large-scale cohort studies are recommended to validate the findings presented in the current study.
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