Evidence map›Paper›PMID 40172770›Full record

ArticleAging clinical and experimental research2025

Handgrip strength as a predictor of one-year mortality in elderly patients with fragility hip fracture.

Francesco Salis, Irene Buffoli, Maristella Belfiori, Alice Bellisai, Benedetta Gianoglio, Giuseppe Marongiu, Monia Marzuolo, Giuseppe Navarra, Veronica Piras, Benedetta Puxeddu and 4 more

Abstract read
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Article in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Francesco Salis *Department of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy. francesco-salis@tiscali.it.ORCID http://orcid.org/0000-0002-4512-9161
Irene Buffoli *Department of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy.
Maristella BelfioriDepartment of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy.
Alice BellisaiDepartment of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy.
Benedetta GianoglioDepartment of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy.
Giuseppe MarongiuDepartment of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Monia MarzuoloDepartment of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy.
Giuseppe NavarraDepartment of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy.
Veronica PirasDepartment of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy.
Benedetta PuxedduDepartment of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy.
Luisa SannaDepartment of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy.
Chiara ScuduDepartment of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy.
Antonio Capone *Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Antonella Mandas *Department of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, Monserrato, Cagliari, 09042, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFragility fractures occur on porotic bones due to minor trauma and are associated with high rates of disability and mortality.

aimsTo evaluate the ability of handgrip strength to predict one-year mortality in elderly patients with fragility hip fracture.

methodsWe enrolled patients aged 65 years and older with fragility hip fractures admitted to an Italian orthopedic unit. They underwent a comprehensive geriatric assessment, including handgrip strength measurement, and all received surgical intervention.

resultsAmong the 322 enrolled patients (median age: 84 years; 75.2% women), the one-year mortality rate was 15.5%. According to the European Working Group on Sarcopenia in Older People 2 guidelines, 235 subjects (73.0%) exhibited low handgrip strength. This group revealed HR: 2.36 (95%CI: 1.06-5.24) for one-year mortality compared to the group with adequate handgrip strength (p = 0.036). After adjusting for age and risk of adverse event, through Multidimensional Prognostic Index, the HR decreased to 1.31 (95%CI: 0.56-3.07), with a lower validity. DISCUSSION: Our study found a slightly lower one-year mortality than other studies with similar samples, probably due to the co-management of orthopedic and geriatric teams. As for the main outcome, low handgrip strength was significantly associated with one-year mortality. However, the significance diminished when considering possible confounding variables, despite a lower precision of the model.

conclusionsLow handgrip strength predicts one-year mortality in elderly people with fragility hip fractures. Further studies are needed to explore the possible influence of confounders.

Indexed as

Hand StrengthHip FracturesAgedAged, 80 and overFemaleGeriatric AssessmentHumansItalyMalePrognosisElderlyFragility fracturesHandgrip strengthMortality

Identifiers

PMID40172770
PMCPMC11965246

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.