Evidence map›Paper›PMID 40172761›Full record

ArticleTropical animal health and production2025

Exploring the impact of chia seeds and matcha green tea on gene expression related to the puberty pathway in growing male New Zealand white rabbits.

Ahmed S H Soliman, Shymaa Sobhy Mourad, Amira Abdalla Abdelshafy Mohamed

Abstract read
In one paragraph

Article in Tropical animal health and production, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ahmed S H SolimanDepartment of Animal Production, Faculty of Agriculture, New Valley University, Al Kharga City, New Valley, Egypt. ahmed.soliman@agr.nvu.edu.eg.ORCID http://orcid.org/0000-0003-0543-8952
Shymaa Sobhy MouradImmunology and Hematology Division, Department of Zoology, Faculty of Science, Arish University, Al-Arish, North- Sinai, 45511, Egypt.ORCID http://orcid.org/0009-0000-0158-3955
Amira Abdalla Abdelshafy Mohamed *Department of Animal Production, Faculty of Environmental Agricultural Sciences, Arish University, Al-Arish, North- Sinai, 45511, Egypt.ORCID http://orcid.org/0000-0002-4519-8132

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abundant direct and in-direct genes are involved in regulating sexual hormones, and reproductive process under nitrite antioxidant plants in rabbit feed. However, there is not enough information about the role of chia seeds and matcha tea as anti-oxidative plants inhibit some direct and in-direct genes related to puberty of growing male rabbits. In this study New-Zealand White (NZW) rabbits treated with chia seeds and matcha tea in water from age after weaning to marketing age about two months ago and determent some sexual hormones, direct and in-direct genes related to puberty and reproduction process. Our data showed total testosterone measured by ELISA increased significantly in chia rabbits compared to control. ELISA analysis revealed that there were no alterations in the levels of follicle stimulating hormone (FSH) and luteinizing hormone (LH) in the treated groups. Direct genes such as doublesex and mab-3 related transcription factor 1 (DMRT1), sex-determining region Y protein (SRY), and gonadotropin-releasing hormone 1 (GnRH1) determent by qPCR show up-regulating in matcha groups comparable to control group. While in-direct genes follicle stimulating hormone receptor (FSHR) and estrogen receptor 1 (ESR1) detected by qPCR showed up-regulated in matcha rabbits compared to control rabbits. But, luteinizing hormone receptor (LHR) gene was down-regulated in matcha group, and it was up-regulated in chia seeds groups. The prolactin receptor (PRLR) gene investigates down-regulation in all treatment groups. Collectively, matcha tea as one of antioxidant plants were involved those genes studied and activated via hypothalamic- pituitary gonadal axis and led to early puberty in growing male NZW rabbits.

Indexed as

Gene ExpressionSalviaSexual MaturationTeaAnimal FeedAnimalsDietFollicle Stimulating HormoneLuteinizing HormoneMaleRabbitsSeedsTestosteroneFollicle Stimulating HormoneLuteinizing HormoneTeaTestosteroneChia seedsGene expressionGrowing rabbitsMatcha tea

Identifiers

PMID40172761
PMCPMC11965149

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.