ArticleDermatology and therapy2025
Impacts of Topical Treatments and Phototherapy on Stratum Corneum Hydration, Sebum and Elasticity in Vitiligo Skin.
Article in Dermatology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- High-pressure microjet system enhances epidermal delivery of hydrophilic actives.Biochemistry and biophysics reports · 2026Article
- Circumscribed Morphea Successfully Treated With Excimer Laser: Analysis of Histopathological Changes.The Journal of dermatology · 2026Article
- Dysregulated Intracellular Signaling in the Pathogenesis of Vitiligo: An Update on Emerging Therapeutic Strategies.Biomedicines · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
introductionVitiligo is a prevalent depigmentation disorder. Due to the depigmentation and treatments, skin function of patients with vitiligo may be affected, manifested by changes in the stratum corneum (SC) hydration, sebum and elasticity. However, few researchers have paid attention to the skin condition of vitiligo after treatment.
methodsA cross-sectional study was conducted. SC hydration, sebum and elasticity of 154 vitiligo lesions were measured to evaluate skin function after topical treatments and phototherapy and investigate potential influencing factors.
resultsTreated vitiligo lesions exhibited significantly lower SC hydration and elasticity compared to normal skin, while sebum levels were notably higher. Combined treatments-specifically, 308-nm excimer laser with topical calcineurin inhibitors (TCI) and either topical corticosteroids (TCS) or compound kaliziran tincture (CKT), as well as 308-nm excimer laser with TCI, TCS and CKT-resulted in reduced SC hydration and elasticity as well as increased sebum levels in lesions. Notably, the 308-nm excimer laser had a greater effect on increasing sebum on lesions.
conclusionOur findings indicate that skin barrier damage and decreased elasticity occur in patients with vitiligo after topical treatments and phototherapy. This underscores the need for enhanced skin management and appropriate post-treatment skin care for patients with vitiligo.
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