Evidence map›Paper›PMID 40172608›Full record

ReviewArchives of gynecology and obstetrics2025

Isolated hydrometrocolpos and cloacal malformation: can we prenatally distinguish them?-A case report and literature review.

Meylign Long, Kaiyu Fu, Jie Ruan

Abstract readCase ReportsReview
In one paragraph

Review in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Meylign Long *Department of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases in Women and Children of Ministry of Education, West China Second Hospital, Sichuan University, Sichuan, 610041, China.
Kaiyu Fu *Department of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases in Women and Children of Ministry of Education, West China Second Hospital, Sichuan University, Sichuan, 610041, China.
Jie RuanDepartment of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases in Women and Children of Ministry of Education, West China Second Hospital, Sichuan University, Sichuan, 610041, China. Isabel0326@163.com.

Funding

Sichuan Provincial Science and Technology Support Program 2023ZYD0117
6 · The paper itself

Abstract

backgroundHydrometrocolpos (HMC) is a rare prenatal ultrasound abnormality, presenting in two distinct types: urinary-type and secretory-type. The urinary variation is intricately linked to cloacal malformation (CM), thereby posing a heightened risk of perinatal adverse events. Additionally, children affected by this type often face long-term challenges that impact their quality of life. Therefore, predicting the presence of CM in HMC fetuses is of great clinical significance. CASE PRESENTATION: We present a case involving hydrometrocolpos accompanied by oligohydramnios. Prenatally, the condition was strongly indicative of CM based on imaging manifestations and intrauterine procedures, a suspicion that was later confirmed through postnatal autopsy.

conclusionDue to the extremely low incidence of HMC, current literature primarily consists of case reports, and there are no studies that comprehensively analyze the prognosis of the disease. This research fills this gap by statistically analyzing the present case as well as 164 prenatal HMC cases reported in the previous literature. Gestational age (GA) at initial detection, the presence of fetal ascites, urinary tract dilatation, anorectal imaging abnormalities, and Müllerian anomalies are meaningful predictors of CM in HMC fetuses. Intrauterine procedures can be used to preserve organ function in complete lower urinary tract obstruction and oligohydramnios secondary to HMC. In addition, biochemical analysis of HMC fluid can differentiate between urinary-type HMC and secretory-type HMC. This study provides valuable insights into the prognostic factors and management strategies for HMC, which could guide clinical decision-making in prenatal care.

Indexed as

CloacaHydrocolposAbnormalities, MultipleAdultFemaleHumansOligohydramniosPregnancyUltrasonography, PrenatalCloacal malformationFetal ascitesHydrometrocolposIntrauterine procedures

Identifiers

PMID40172608
PMCPMC12033211

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.