Evidence map›Paper›PMID 40172537›Full record

ArticleInfection and immunity2025

The unique histidine kinase, AtcS, regulates motility and pathogenicity of the periodontal pathobiont,

Doaa N Abdallah, Annie N Hinson, Aidan D Moylan, Dhara T Patel, Bin Zhu, Richard T Marconi, Daniel P Miller

Abstract read
In one paragraph

Article in Infection and immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Doaa N Abdallah *Department of Microbiology and Immunology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Annie N Hinson *Department of Microbiology and Immunology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Aidan D MoylanDepartment of Microbiology and Immunology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Dhara T PatelDepartment of Microbiology and Immunology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Bin ZhuMassey Comprehensive Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.
Richard T MarconiDepartment of Microbiology and Immunology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-6035-7306
Daniel P MillerDepartment of Microbiology and Immunology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-1332-5870

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Renato Martins · 1985 to 2026
$51.0M
Two-component signaling systems of Treponema denticolaR01DE033722 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI Daniel Patrick Miller · 2024 to 2026
$1.1M
Polymicrobial Synergy between Treponema denticola and Porphyromonas gingivalisR00DE028346 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI MILLER, DANIEL PATRICK · 2020 to 2022
$747k
NCI NIH HHS P30 CA016059NIDCR NIH HHS R00 DE028346NIDCR NIH HHS R01 DE033722NIDCR NIH HHS R01DE033722
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ProteinsHistidine KinaseTreponema denticolaAnimalsGene DeletionGene Expression Regulation, BacterialHumansMicePeriodontal DiseasesPeriodontitisTreponemal InfectionsVirulenceBacterial ProteinsHistidine Kinasehistidine kinaseperiodontitisspirochetesTreponemaTreponema denticolatwo-component regulatory systems

Identifiers

PMID40172537
PMCPMC12070737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.