ArticleRevista da Associacao Medica Brasileira (1992)2025
Vitamin D and thyroid function of pregnant women in a sunny region: is there any connection?
Article in Revista da Associacao Medica Brasileira (1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Development and validation of an interpretable machine learning model for predicting incident gestational hypothyroidism using clinical laboratory markers.Frontiers in medicine · 2026Article
- Regarding the vitamin D and thyroid function of pregnant women in a sunny region, is there any connection?Revista da Associacao Medica Brasileira (1992) · 2026Article
- A detailed nutritional assessment may further elucidate the relationship between vitamin D and thyroid function.Revista da Associacao Medica Brasileira (1992) · 2025Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to investigate the relationship between vitamin D serum concentrations and thyroid hormones of pregnant women living in a sunny region of Northeast Brazil.
methodsThis is a cross-sectional secondary analysis of a study that evaluated the iodine status of pregnant women attending prenatal consultations in a tertiary hospital. Consecutive patients (>18 years) were conveniently sampled. Blood samples were collected for the study, including measurements of vitamin D, anti-TPO, and anti-Tg antibodies, thyroid-stimulating hormone, total and free thyroxine (TT4, FT4), and total and free triiodothyronine (TT3, FT3). Vitamin D levels <20 ng/mL were considered deficient. Between 20 and 30 ng/mL were classified as insufficient, and >30 ng/mL were sufficient. Additional data on urinary iodine concentrations, anthropometry, sociodemographic, and gestational features were also collected.
resultsA total of 562 pregnant women were included, with a median age of 29 years. Most of them (47.9%) were in the first gestational semesters. Only 3.9% of subjects presented with vitamin D deficiency, while 81% had insufficient values and 15.1% had sufficient levels. Vitamin D levels were not significantly correlated or associated with thyroid hormones or body mass index (all p-values >0.05).
conclusionOur study adds to the growing body of evidence highlighting the importance of assessing the status of both vitamin D and thyroid hormones in population- and region-specific contexts, as it may vary accordingly.
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