ArticleRevista brasileira de enfermagem2025
Outcome measures reported by cancer patients treated with tyrosine kinase inhibitors: a methodological study.
Article in Revista brasileira de enfermagem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
5 authors.
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Abstract
objectivesto validate the content of an outcome measurement instrument with expert judges and to assess the understandability and suitability of this validated instrument with cancer patients undergoing tyrosine kinase inhibitor (TKI) therapy.
methodsa methodological study, which included the development of an instrument through integrative review, content validity, using the Delphi technique with expert judges, and pilot testing, to verify users' understandability and suitability to the instrument.
resultsliterature review allowed constructing PRO-CTCAE® Estudo PROM-TKI Brasil, with 16 items, which was later submitted to validity using the Delphi technique. After the second round, the final instrument consisted of 20 items, with a Content Validity Index (CVI) of 0.878. The pilot test showed that the instrument is understandable and suitable for the target population (CVI of 1.0).
conclusionsPRO-CTCAE® Estudo PROM-TKI Brasil obtained evidence of validity for use during TKI therapy.
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