Evidence map›Paper›PMID 40171773›Full record

SynthesisActa odontologica Scandinavica2025

Prevalence of bruxism in patients affected by epilepsy: a systematic review and meta-analysis.

Giuseppe Minervini, Rocco Franco, Marco Di Blasio, Mirko Martelli, Marco Gargari, Patrizio Bollero, Marco Cicciù

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Acta odontologica Scandinavica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giuseppe MinerviniSaveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India; Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania 'Luigi Vanvitelli', Naples, Italy.
Rocco FrancoDepartment of Biomedicine and Prevention, University of Rome 'Tor Vergata', Rome, Italy.
Marco Di BlasioDepartment of Biomedical Surgical and Dental Sciences, University of Milan, Milan, Italy. marco.diblasio@unimi.it.
Mirko MartelliDepartment of Clinical Sciences and Translational Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Marco GargariDepartment of Clinical Sciences and Translational Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Patrizio BolleroDepartment of System Medicine, University of Rome Tor Vergata, Rome, Italy.
Marco CicciùDepartment of Biomedical and Surgical and Biomedical Sciences, Catania University, Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBruxism, defined by the involuntary grinding or clenching of teeth, and epilepsy, a neurological ailment marked by recurring seizures, are both common conditions that can significantly affect persons' quality of life. Although numerous studies have investigated the relationship between bruxism and epilepsy, the current evidence is ambiguous. This systematic review seeks to consolidate existing information to elucidate the association between bruxism and epilepsy.

methodsIn accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline, a systematic search was performed across electronic databases, including PubMed, Lilacs, and Web of Science. The search encompassed all pertinent publications published until September 2021. The inclusion criteria were established to encompass observational studies (cohort, case-control, cross-sectional) that investigated the relationship between bruxism and epilepsy in human populations.

resultsThe preliminary search produced a total of 142 articles. After a rigorous screening process, 3 studies were declared appropriate for inclusion in the systematic review. The research varied in design, sample size, and methodology, with some studying the prevalence of bruxism in epileptic patients, while others studied the prevalence of epilepsy in individuals with bruxism. Heterogeneity among the research was handled using proper statistical analyses.

conclusionThe findings from the included studies suggested a probable link between bruxism and epilepsy. However, the evidence was uneven and equivocal, with some research indicating a favourable correlation, while others showed no meaningful relationship. Methodological restrictions, such as changes in diagnostic criteria and data collection procedures, could contribute to the observed inconsistencies. In addition, the possible influence of confounding factors, such as medication use and comorbidities, should be addressed in interpreting the data.

Indexed as

BruxismEpilepsyHumansPrevalence

Identifiers

PMID40171773
PMCPMC12056371

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.